Setting Standards for Reporting and Quantification in Fluorescence-Guided Surgery.
Purpose: Intraoperative fluorescence imaging (FI) is a promising technique that could potentially guide oncologic surgeons toward more radical resections and thus improve clinical outcome. Despite the increase in the number of clinical trials, fluorescent agents and imaging systems for intraoperativ...
| Publicado en: | Molecular Imaging & Biology Vol. 21; no. 1; pp. 11 - 19 |
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| Autores principales: | , , , , , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134786714&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134786714 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15361632 KJU jtl: Molecular Imaging & Biology issn: 15361632 maglogo: N pubinfo: dt: Feb2019 vid: 21 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 134786714 134786714 NLM29845427 134786714 10.1007/s11307-018-1220-0 NLM29845427 134786714 ppf: 11 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Setting Standards for Reporting and Quantification in Fluorescence-Guided Surgery. aug: au: Hoogstins, Charlotte Burggraaf, Jan Jaap Koller, Marjory Handgraaf, Henricus Boogerd, Leonora van Dam, Gooitzen Vahrmeijer, Alexander Burggraaf, Jacobus affil: Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2333, Leiden, ZA, the Netherlands sug: subj: Image Processing, Computer Assisted Equipment and Supplies Practice Guidelines Diagnostic Imaging Standards Intraoperative Monitoring Equipment and Supplies Intraoperative Monitoring Standards Intraoperative Monitoring Methods Diagnostic Imaging Methods Surgery, Computer-Assisted Methods Surgery, Computer-Assisted Standards Image Processing, Computer Assisted Standards Image Processing, Computer Assisted Methods Calibration Neoplasms Pathology Neoplasms Surgery Reproducibility of Results Neoplasms Diagnosis Study Design Standards Risk Assessment Standards Sensitivity and Specificity Surgery, Computer-Assisted Equipment and Supplies Human Weights and Measures Animal Studies Diagnostic Imaging Equipment and Supplies Validation Studies Comparative Studies Evaluation Research Multicenter Studies ab: Purpose: Intraoperative fluorescence imaging (FI) is a promising technique that could potentially guide oncologic surgeons toward more radical resections and thus improve clinical outcome. Despite the increase in the number of clinical trials, fluorescent agents and imaging systems for intraoperative FI, a standardized approach for imaging system performance assessment and post-acquisition image analysis is currently unavailable.Procedures: We conducted a systematic, controlled comparison between two commercially available imaging systems using a novel calibration device for FI systems and various fluorescent agents. In addition, we analyzed fluorescence images from previous studies to evaluate signal-to-background ratio (SBR) and determinants of SBR.Results: Using the calibration device, imaging system performance could be quantified and compared, exposing relevant differences in sensitivity. Image analysis demonstrated a profound influence of background noise and the selection of the background on SBR.Conclusions: In this article, we suggest clear approaches for the quantification of imaging system performance assessment and post-acquisition image analysis, attempting to set new standards in the field of FI. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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