SBRT-Planung bei Wirbelsäulenmetastasen: Indikationen aus einer großen Multizenterstudie.
Background: The dosimetric variability in spine stereotactic body radiation therapy (SBRT) planning was investigated in a large number of centres to identify crowd knowledge-based solutions.Methods: Two spinal cases were planned by 48 planners (38 centres). The required prescription dose (PD) was 3 ...
| Published in: | Strahlentherapie und Onkologie Vol. 195; no. 3; pp. 226 - 236 |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Mar2019
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134830984&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134830984 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01797158 NZE jtl: Strahlentherapie und Onkologie issn: 01797158 maglogo: N pubinfo: dt: Mar2019 vid: 195 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 134830984 134830984 NLM30353349 134830984 10.1007/s00066-018-1383-2 NLM30353349 134830984 ppf: 226 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: SBRT-Planung bei Wirbelsäulenmetastasen: Indikationen aus einer großen Multizenterstudie. aug: au: Esposito, Marco Masi, Laura Zani, Margherita Doro, Raffaela Fedele, David Garibaldi, Cristina Clemente, Stefania Fiandra, Christian Giglioli, Francesca Romana Marino, Carmelo Orsingher, Laura Russo, Serenella Stasi, Michele Strigari, Lidia Villaggi, Elena Mancosu, Pietro affil: Medical Physics Complex Unit, Azienda USL Toscana Centro, Via dell'Antella 58, 50012, Bagno a Ripoli, Italy sug: subj: Radiotherapy, Computer-Assisted Methods Radiotherapy, Conformal Methods Radiometry Spinal Neoplasms Spinal Neoplasms Radiotherapy Radiosurgery Methods Human Spinal Cord Radiation Effects Body Regions Radiation Effects Clinical Competence Quality Assurance Methods Radiation Injuries Prevention and Control Validation Studies Comparative Studies Evaluation Research Multicenter Studies Ferrans and Powers Quality of Life Index Impact of Events Scale ab: Background: The dosimetric variability in spine stereotactic body radiation therapy (SBRT) planning was investigated in a large number of centres to identify crowd knowledge-based solutions.Methods: Two spinal cases were planned by 48 planners (38 centres). The required prescription dose (PD) was 3 × 10 Gy and the planning target volume (PTV) coverage request was: VPD > 90% (minimum request: VPD > 80%). The dose constraints were: planning risk volume (PRV) spinal cord: V18Gy < 0.35 cm3, V21.9 Gy < 0.03 cm3; oesophagus: V17.7 Gy < 5 cm3, V25.2 Gy < 0.03 cm3. Planners who did not fulfil the protocol requirements were asked to re-optimize the plans, using the results of planners with the same technology. Statistical analysis was performed to assess correlations between dosimetric results and planning parameters. A quality index (QI) was defined for scoring plans.Results: In all, 12.5% of plans did not meet the protocol requirements. After re-optimization, 98% of plans fulfilled the constraints, showing the positive impact of knowledge sharing. Statistical analysis showed a significant correlation (p < 0.05) between the homogeneity index (HI) and PTV coverage for both cases, while the correlation between HI and spinal cord sparing was significant only for the single dorsal PTV case. Moreover, the multileaf collimator leaf thickness correlated with the spinal cord sparing. Planners using comparable delivery/planning system techniques produced different QI, highlighting the impact of the planner's skills in the optimization process.Conclusion: Both the technology and the planner's skills are fundamentally important in spine SBRT planning optimization. Knowledge sharing helped to follow the plan objectives. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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