Validation of the Patient-Reported Outcomes Measurement Information System (PROMIS)-57 and -29 item short forms among kidney transplant recipients.

Objective: The Patient-Reported Outcomes Measurement Information System (PROMIS) aims to address the lack of generalizable and universal measure of patient-reported outcomes to assess health-related quality of life. It has not been validated for patients with chronic kidney disease. We aim to valida...

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Publicado en:Quality of Life Research Vol. 28; no. 3; pp. 815 - 828
Autores principales: Tang, Evan, Ekundayo, Oladapo, Peipert, John Devin, Edwards, Nathaniel, Bansal, Aarushi, Richardson, Candice, Bartlett, Susan J., Howell, Doris, Li, Madeline, Cella, David, Novak, Marta, Mucsi, Istvan
Formato: Journal Article
Publicado: Springer Nature Mar2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2019
      vid: 28
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11136-018-2058-2
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        atl: Validation of the Patient-Reported Outcomes Measurement Information System (PROMIS)-57 and -29 item short forms among kidney transplant recipients.
      aug:
        au:
          Tang, Evan
          Ekundayo, Oladapo
          Peipert, John Devin
          Edwards, Nathaniel
          Bansal, Aarushi
          Richardson, Candice
          Bartlett, Susan J.
          Howell, Doris
          Li, Madeline
          Cella, David
          Novak, Marta
          Mucsi, Istvan
        affil: Division of Nephrology, Multi-Organ Transplant Program, University Health Network and University of Toronto, Toronto, Canada
      sug:
        subj:
          Kidney Transplantation Methods
          Quality of Life Psychosocial Factors
          Renal Insufficiency, Chronic Surgery
          Female
          Cross Sectional Studies
          Male
          Reproducibility of Results
          Middle Age
          Questionnaires
          Scales
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: The Patient-Reported Outcomes Measurement Information System (PROMIS) aims to address the lack of generalizable and universal measure of patient-reported outcomes to assess health-related quality of life. It has not been validated for patients with chronic kidney disease. We aim to validate the PROMIS-57 and PROMIS-29 questionnaires among kidney transplant recipients.Methods: A cross-sectional sample of stable kidney transplant recipients was recruited. Each participant completed PROMIS-57, a 57-question instrument covering seven domains-physical function, anxiety, depression, fatigue, pain, sleep disturbance, and social functioning-alongside validated legacy questionnaires [Patient Health Questionnaire (PHQ9), General Anxiety Disorder (GAD7), Edmonton Symptom Assessment Scale revised (ESASr), and Kidney Disease Quality of Life (KDQoL-36)]. PROMIS-29, a 29-question instrument, is nested within PROMIS-57 and measures the same domains. Structural validity of PROMIS was assessed with confirmatory factor analysis, reported using the Comparative Fit Index (CFI). Construct validity was assessed with known-groups comparisons. Internal consistency was evaluated with Cronbach's α and convergent validity was assessed with Spearman's Rho. Test-retest reliability was assessed through the intraclass correlation coefficient (ICC).Results: Mean (± SD) age of the 177 participants was 50 (± 17), 57% were male and 55% Caucasian. Internal consistency of each domain was high (Cronbach's α > 0.88). Confirmatory factor analysis showed good structural validity for most domains (CFI > 0.95, RMSEA < 0.05). Test-retest reliability indicated good agreement (ICC > 0.6). Known-groups comparisons by clinical and socio-demographic differences were found as hypothesized.Conclusions: Our results provide evidence that PROMIS-57 and PROMIS-29 are highly reliable and valid instruments among kidney transplant recipients. We propose it as a valuable tool to assess important domains of the illness experience.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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