In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice.
The traditional surgical pathology assessment requires tissue to be removed from the patient, then processed, sectioned, stained, and interpreted by a pathologist using a light microscope. Today, an array of alternate optical imaging technologies allow tissue to be viewed at high resolution, in real...
| Publicado en: | Archives of Pathology & Laboratory Medicine Vol. 143; no. 3; pp. 288 - 299 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | diagnostic images pictorial review tables/charts Journal Article |
| Publicado: |
College of American Pathologists
Mar2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135037034&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135037034 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00039985 1FS jtl: Archives of Pathology & Laboratory Medicine issn: 00039985 maglogo: N pubinfo: dt: Mar2019 vid: 143 iid: 3 pid: 2550 pub: College of American Pathologists place: Northfield, Illinois artinfo: ui: 135037034 135037034 135037034 10.5858/arpa.2018-0298-RA 135037034 ppf: 288 ppct: 11 formats: fmt: @attributes: type: P tig: atl: In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice. aug: au: Wells, Wendy A. Thrall, Michael Sorokina, Anastasia Fine, Jeffrey Krishnamurthy, Savitri Haroon, Attiya Rao, Babar Shevchuk, Maria M. Wolfsen, Herbert C. Tearney, Guillermo J. Hariri, Lida P. affil: Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire sug: subj: Microscopy Methods Tomography Methods Technology Diagnostic Imaging Pathologists Adaptation, Occupational Attitude to Change Professional Practice ab: The traditional surgical pathology assessment requires tissue to be removed from the patient, then processed, sectioned, stained, and interpreted by a pathologist using a light microscope. Today, an array of alternate optical imaging technologies allow tissue to be viewed at high resolution, in real time, without the need for processing, fixation, freezing, or staining. Optical imaging can be done in living patients without tissue removal, termed in vivo microscopy, or also in freshly excised tissue, termed ex vivo microscopy. Both in vivo and ex vivo microscopy have tremendous potential for clinical impact in a wide variety of applications. However, in order for these technologies to enter mainstream clinical care, an expert will be required to assess and interpret the imaging data. The optical images generated from these imaging techniques are often similar to the light microscopic images that pathologists already have expertise in interpreting. Other clinical specialists do not have this same expertise in microscopy, therefore, pathologists are a logical choice to step into the developing role of microscopic imaging expert. Here, we review the emerging technologies of in vivo and ex vivo microscopy in terms of the technical aspects and potential clinical applications. We also discuss why pathologists are essential to the successful clinical adoption of such technologies and the educational resources available to help them step into this emerging role. pubtype: Academic Journal doctype: diagnostic images pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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