Impact of demographic disparities in social distancing and vaccination on influenza epidemics in urban and rural regions of the United States.

Background: Self-protective behaviors of social distancing and vaccination uptake vary by demographics and affect the transmission dynamics of influenza in the United States. By incorporating the socio-behavioral differences in social distancing and vaccination uptake into mathematical models of inf...

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Publicado en:BMC Infectious Diseases Vol. 19; no. 1
Autores principales: Singh, Meghendra, Sarkhel, Prasenjit, Kang, Gloria J., Marathe, Achla, Boyle, Kevin, Murray-Tuite, Pamela, Abbas, Kaja M., Swarup, Samarth
Formato: equations & formulas research tables/charts Journal Article
Publicado: BioMed Central 3/4/2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 3/4/2019
      vid: 19
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      pub: BioMed Central
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        10.1186/s12879-019-3703-2
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        atl: Impact of demographic disparities in social distancing and vaccination on influenza epidemics in urban and rural regions of the United States.
      aug:
        au:
          Singh, Meghendra
          Sarkhel, Prasenjit
          Kang, Gloria J.
          Marathe, Achla
          Boyle, Kevin
          Murray-Tuite, Pamela
          Abbas, Kaja M.
          Swarup, Samarth
        affil: Network Dynamics and Simulation Science Laboratory, Biocomplexity Institute of Virginia Tech, 24060, Blacksburg, Virginia, USA
      sug:
        subj:
          Social Distancing
          Influenza Vaccine Immunology
          Influenza, Human Prevention and Control
          Influenza, Human Epidemiology
          Health Behavior
          Adult
          Aged
          Young Adult
          Female
          Immunization
          United States
          Disease Outbreaks
          Models, Theoretical
          Urban Population
          Adolescence
          Rural Population
          Male
          Middle Age
          Impact of Events Scale
          Social Readjustment Rating Scale
          Funding Source
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: Self-protective behaviors of social distancing and vaccination uptake vary by demographics and affect the transmission dynamics of influenza in the United States. By incorporating the socio-behavioral differences in social distancing and vaccination uptake into mathematical models of influenza transmission dynamics, we can improve our estimates of epidemic outcomes. In this study we analyze the impact of demographic disparities in social distancing and vaccination on influenza epidemics in urban and rural regions of the United States.Methods: We conducted a survey of a nationally representative sample of US adults to collect data on their self-protective behaviors, including social distancing and vaccination to protect themselves from influenza infection. We incorporated this data in an agent-based model to simulate the transmission dynamics of influenza in the urban region of Miami Dade county in Florida and the rural region of Montgomery county in Virginia.Results: We compare epidemic scenarios wherein the social distancing and vaccination behaviors are uniform versus non-uniform across different demographic subpopulations. We infer that a uniform compliance of social distancing and vaccination uptake among different demographic subpopulations underestimates the severity of the epidemic in comparison to differentiated compliance among different demographic subpopulations. This result holds for both urban and rural regions.Conclusions: By taking into account the behavioral differences in social distancing and vaccination uptake among different demographic subpopulations in analysis of influenza epidemics, we provide improved estimates of epidemic outcomes that can assist in improved public health interventions for prevention and control of influenza.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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