No effect of attentional bias modification training in methamphetamine users receiving residential treatment.
Rationale: Attentional bias toward drug-related stimuli is a feature of drug addiction that is linked to craving and drug-seeking behavior.Objectives/method: An attentional bias modification (ABM) program was tested in 42 methamphetamine-dependent clients (DSM-IV criteria) receiving residential trea...
| Publicado en: | Psychopharmacology Vol. 236; no. 2; pp. 709 - 722 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Feb2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135086342&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135086342 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00333158 EJD jtl: Psychopharmacology issn: 00333158 maglogo: N pubinfo: dt: Feb2019 vid: 236 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 135086342 10.1007/s00213-018-5100-8 135086342 ppf: 709 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: No effect of attentional bias modification training in methamphetamine users receiving residential treatment. aug: au: Dean, Andy C. Nurmi, Erika L. Moeller, Scott J. Amir, Nader Rozenman, Michelle Ghahremani, Dara G. Johnson, Maritza Berberyan, Robert Hellemann, Gerhard Zhang, Ziwei London, Edythe D. affil: Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, 90024, Los Angeles, CA, USA sug: ab: Rationale: Attentional bias toward drug-related stimuli is a feature of drug addiction that is linked to craving and drug-seeking behavior.Objectives/method: An attentional bias modification (ABM) program was tested in 42 methamphetamine-dependent clients (DSM-IV criteria) receiving residential treatment for their drug use. Participants were randomly assigned to one of two groups (N = 21 each), receiving 12 sessions of either computerized ABM training (designed to train attention away from methamphetamine stimuli 100% of the time) or an attentional control condition (designed to train attention away from methamphetamine stimuli 50% of the time). Outcome measures included attentional bias to methamphetamine-related stimuli on a probe detection task, self-reported craving, and preferences to view methamphetamine-related images on a Simulated Drug Choice Task. A subset of participants (N = 17) also underwent fMRI in a cue-induced craving paradigm.Results: Poor split-half reliability was observed for the probe detection task. Using this task, attentional bias toward methamphetamine-related stimuli was greater after training than at baseline, irrespective of group (p = 0.037). Spontaneous and cue-induced methamphetamine craving diminished with time (ps < 0.01), but ABM training did not influence these effects (group by time interactions, ps > 0.05). ABM training did not influence selection of methamphetamine-related pictures in the Simulated Drug Choice task (p > 0.05). In the fMRI assessment, cue-induced activation in the ventromedial prefrontal cortex was reduced over time, without an effect of ABM training.Conclusions: ABM training did not improve several clinically relevant variables in treatment-seeking methamphetamine users. Additional research is needed to improve the measurement of attentional bias. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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