The Effects of Omega-3 on Liver Damage after Acute Myocardial Infarction: A Randomized Controlled Clinical Trial.
Background: Abnormal liver function test results are often observed in patients with acute Myocardial Infarction (MI). Objectives: This study aimed to evaluate the effects of omega-3 fatty acids on Alanine Aminotransferase (ALT) activity elevation after MI-induced liver injury. Methods: In this rand...
| Publicado en: | International Cardiovascular Research Journal Vol. 13; no. 1; pp. 5 - 11 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Brieflands
Mar2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135231339&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135231339 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 22519130 FBPD jtl: International Cardiovascular Research Journal issn: 22519130 maglogo: N pubinfo: dt: Mar2019 vid: 13 iid: 1 pid: 69510 pub: Brieflands place: , <Blank> artinfo: ui: 135231339 135231339 135231339 135231339 ppf: 5 ppct: 6 formats: fmt: @attributes: type: P tig: atl: The Effects of Omega-3 on Liver Damage after Acute Myocardial Infarction: A Randomized Controlled Clinical Trial. aug: au: Moghimian, Maryam Abtahi-Eivary, Seyed-Hosein Nematollahi, Mahmood Reza Ebadi, Abbas Alami, Ali Bahri, Narjes affil: Department of Basic Sciences, School of Medicine, Gonabad University of Medical Sciences, Gonabad, IR Iran sug: subj: Fatty Acids, omega-3 Pharmacodynamics Liver Drug Effects Alanine Aminotransferase Drug Effects Alanine Aminotransferase Blood Myocardial Infarction Complications Liver Diseases Etiology Human Acute Disease Randomized Controlled Trials Fish Oils Patient Admission Data Analysis Software Dietary Supplementation ab: Background: Abnormal liver function test results are often observed in patients with acute Myocardial Infarction (MI). Objectives: This study aimed to evaluate the effects of omega-3 fatty acids on Alanine Aminotransferase (ALT) activity elevation after MI-induced liver injury. Methods: In this randomized clinical trial, 75 patients with acute MI were randomly allocated to an intervention and a control group. The intervention group received 1 gram per day equal to three capsules of Pikasol (fish oil) for three months, while the control group received the routine treatment after MI. In all samples, plasma concentrations of ALT were assessed on the admission day and 2, 30, 60, and 90 days after the intervention. The data were analyzed using the SPSS 16 software, and P < 0.05 was set as the level of statistical significance. Results: The results showed no significant differences between the two groups regarding age, sex, Body Mass Index (BMI), and systolic and diastolic blood pressure. The results also indicated no significant differences between the two groups concerning the serum level of ALT on the day of admission (P = 0.68), day 2 (P = 0.79), day 30 (P = 0.86), day 60 (P = 0.09), and day 90 (P = 0.64). Conclusion: The study results suggested that the patients receiving omega-3 supplementation following MI had similar ALT levels to those who received no supplementations. However, further studies with larger sample sizes are needed to confirm the results. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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