Behavior of leadless AV synchronous pacing during atrial arrhythmias and stability of the atrial signals over time—Results of the MARVEL Evolve subanalysis.
Introduction: The MARVEL study demonstrated at a single time point that accelerometer (ACC)‐based atrial sensing improves atrioventricular (AV) synchrony (AVS) in patients with AV block and a Micra pacemaker (Medtronic, Minneapolis, MN, USA). The purpose of the MARVEL Evolve substudy was to assess t...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 42; no. 3; pp. 381 - 388 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2019
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135292408&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135292408 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Mar2019 vid: 42 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 135292408 135292408 135292408 10.1111/pace.13615 135292408 ppf: 381 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Behavior of leadless AV synchronous pacing during atrial arrhythmias and stability of the atrial signals over time—Results of the MARVEL Evolve subanalysis. aug: au: Garweg, Christophe Splett, Vincent Sheldon, Todd J. Chinitz, Larry Ritter, Philippe Steinwender, Clemens Lemme, Francesca Willems, Rik affil: Department of Cardiovascular Sciences, University of Leuven, Leuven Belgium sug: subj: Heart Block Therapy Cardiac Pacing, Artificial Accelerometers Evaluation Pacemaker, Artificial Evaluation Cardiac Resynchronization Therapy Prospective Studies Male Female Aged Aged, 80 and Over Bradycardia Office Visits Sinoatrial Node Physiology Confidence Intervals Tachycardia Atrial Fibrillation Atrial Flutter Human Aged: 65+ years Aged, 80 & over Male Female ab: Introduction: The MARVEL study demonstrated at a single time point that accelerometer (ACC)‐based atrial sensing improves atrioventricular (AV) synchrony (AVS) in patients with AV block and a Micra pacemaker (Medtronic, Minneapolis, MN, USA). The purpose of the MARVEL Evolve substudy was to assess the performance over time. Methods: This prospective single‐center study compared AVS and ACC signals at two visits ≥6 months apart. Custom software was temporarily downloaded into the Micra at each visit and AVS was measured during 30 min at rest. Results: Nine patients from the MARVEL study were enrolled. The mean (±standard deviation) age was 82.3 ± 6.0 years old, 67% were male, and a Micra was implanted for 6.0 ± 6.4 months. High‐degree AV block was present in four patients, whereas five with predominantly intrinsic conduction required intermittent pacing for bradycardia. The mean interval between visits was 7.1 ± 0.6 months. Seven patients had normal sinus node function at both visits and were included in a paired analysis. Both ACC signal amplitude (visit 2‐visit 1 = 1.4 mG; 95% confidence interval [CI] [−25.8 to 28.4 mG]; P = 0.933) and AVS (visit 1: 90.8%, 95% CI [72.4, 97.4] and visit 2: 91.4%, 95% CI [63.8, 98.5]; P = 0.740) remained stable. Three patients had spontaneous atrial tachycardia. During atrial fibrillation, no atrial contraction was detected or tracked. During atrial flutter, intermittent tracking resulted in a ventricular rate of 60 ± 8 beats per minute (bpm); there was no ventricular pacing >100 bpm. Conclusion: ACC signals amplitude and performance of AVS pacing were stable over time. During atrial arrhythmias, the AV synchronous pacing mode behaved safely. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|