Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field.
The integration of genomic data into screening, prevention, diagnosis, and treatment for clinical and public health practices has been slow and challenging. Implementation science can be applied in tackling the barriers and challenges as well as exploring opportunities and best practices for integra...
| Publicado en: | Ethnicity & Disease Vol. 29; pp. 187 - 193 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
KnowledgeWorks Global, Ltd
2019 Supplement
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135299439&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135299439 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1049510X 2QJY jtl: Ethnicity & Disease issn: 1049510X maglogo: N pubinfo: dt: 2019 Supplement vid: 29 pid: 81084 pub: KnowledgeWorks Global, Ltd place: Richmond, Virginia artinfo: ui: 135299439 135299439 NLM30906168 10.18865//ed.29.s1.187 NLM30906168 135299439 ppf: 187 ppct: 6 formats: tig: atl: Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field. aug: au: Roberts, Megan C. Mensah, George A. Khoury, Muin J. affil: Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina sug: subj: Research, Medical Genomics Methods Research, Medical Methods Public Health Standards Public Health Methods Quality Improvement Professional Practice, Evidence-Based Methods Impact of Events Scale Scales ab: The integration of genomic data into screening, prevention, diagnosis, and treatment for clinical and public health practices has been slow and challenging. Implementation science can be applied in tackling the barriers and challenges as well as exploring opportunities and best practices for integrating genomic data into routine clinical and public health practice.In this article, we define the state of disparities in genomic medicine and focus predominantly on late-stage research findings. We use case studies from genetic testing for cardiovascular diseases (familial hypercholesterolemia) and cancer (Lynch syndrome and hereditary breast and ovarian cancer syndrome) in high-risk populations to consider current disparities and related barriers in turning genomic advances into population health impact to advance health equity. Finally, we address how implementation science can address these translational barriers and we discuss the strategic importance of collaborative multi-stakeholder approaches that engage public health agencies, professional societies, academic health and research centers, community clinics, and patients and their families to work collectively to improve population health and reduce or eliminate health inequities. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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