Pyoderma Gangrenosum: A Review for the Gastroenterologist.

Pyoderma gangrenosum (PG) is a rare ulcerative skin disease of unknown etiology often associated with systemic inflammatory conditions, most commonly inflammatory bowel disease (IBD). The most common presentation of PG is spontaneous rapid formation of an extremely painful ulcer on the extremities,...

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Publicado en:Inflammatory Bowel Diseases Vol. 24; no. 12; pp. 2510 - 2518
Autores principales: Plumptre, Isabella, Knabel, Daniel, Tomecki, Kenneth
Formato: pictorial review tables/charts Journal Article
Publicado: Oxford University Press / USA Dec2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2018
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      pub: Oxford University Press / USA
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        atl: Pyoderma Gangrenosum: A Review for the Gastroenterologist.
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        au:
          Plumptre, Isabella
          Knabel, Daniel
          Tomecki, Kenneth
        affil: London North West University Healthcare NHS Trust, London, United Kingdom
      sug:
        subj:
          Pyoderma Gangrenosum
          Inflammatory Bowel Diseases Complications
          Gastroenterologists Education
          Pyoderma Gangrenosum Physiopathology
          Pyoderma Gangrenosum Therapy
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Symptoms
          Pyoderma Gangrenosum Mortality
          Morbidity
          Postoperative Complications
          Surgical Wound
          Immunosuppressive Agents Therapeutic Use
          Disease Management
      ab: Pyoderma gangrenosum (PG) is a rare ulcerative skin disease of unknown etiology often associated with systemic inflammatory conditions, most commonly inflammatory bowel disease (IBD). The most common presentation of PG is spontaneous rapid formation of an extremely painful ulcer on the extremities, associated with significant morbidity and mortality. Rarely, PG can also occur as a chronic peristomal complication or as an acute postoperative complication of a surgical wound. The clinical course is unpredictable; it may not correlate with IBD activity and may even precede a diagnosis of IBD. Pyoderma gangrenosum is a diagnosis of exclusion. Treatment is challenging, often involving a variety of immunosuppressive therapies. This review aims to provide an update for the gastroenterologist on the pathogenesis, presentation, diagnosis, and management of PG, a rare complication of IBD.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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