False positives in PIRADS (V2) 3, 4, and 5 lesions: relationship with reader experience and zonal location.
Purpose: To investigate the effect of reader experience and zonal location on the occurrence of false positives (FPs) in PIRADS (V2) 3, 4, and 5 lesions on multiparametric (MP)-MRI of the prostate.Materials and methods: This retrospective study included 139 patients who had consecutively undergone a...
| Publicado en: | Abdominal Radiology Vol. 44; no. 3; pp. 1044 - 1052 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Mar2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135395028&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135395028 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Mar2019 vid: 44 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 135395028 10.1007/s00261-019-01919-2 135395028 ppf: 1044 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: False positives in PIRADS (V2) 3, 4, and 5 lesions: relationship with reader experience and zonal location. aug: au: Stolk, Tineke T. de Jong, Igle Jan Kwee, Thomas C. Luiting, Henk B. Mahesh, Shekar V. K. Doornweerd, Benjamin H. J. Willemse, Peter-Paul M. Yakar, Derya affil: Department of Radiology, University Medical Center Groningen, Hanzeplein 1, 9700 CC, Groningen, The Netherlands sug: ab: Purpose: To investigate the effect of reader experience and zonal location on the occurrence of false positives (FPs) in PIRADS (V2) 3, 4, and 5 lesions on multiparametric (MP)-MRI of the prostate.Materials and methods: This retrospective study included 139 patients who had consecutively undergone an MP-MRI of the prostate in combination with a transrectal ultrasound MRI fusion-guided biopsy between 2014 and 2017. MRI exams were prospectively read by a group of inexperienced radiologists (cohort 1; 54 patients) and an experienced radiologist (cohort 2; 85 patients). Multivariable logistic regression analysis was performed to determine the association of experience of the radiologist and zonal location with a FP reading. FP rates were compared between readings by inexperienced and experienced radiologists according to zonal location, using Chi-square (χ2) tests.Results: A total of 168 lesions in 139 patients were detected. Median patient age was 68 years (Interquartile range (IQR) 62.5-73), and median PSA was 10.9 ng/mL (IQR 7.6-15.9) for the entire patient cohort. According to multivariable logistic regression, inexperience of the radiologist was significantly (P = 0.044, odds ratio 1.927, 95% confidence interval [CI] 1.017-3.651) and independently associated with a FP reading, while zonal location was not (P = 0.202, odds ratio 1.444, 95% CI 0.820-2.539). In the transition zone (TZ), the FP rate of the inexperienced radiologists 59% (17/29) was significantly higher (χ2P = 0.033) than that of the experienced radiologist 33% (13/40).Conclusion: Inexperience of the radiologist is significantly and independently associated with a FP reading, while zonal location is not. Inexperienced radiologists have a significantly higher FP rate in the TZ. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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