A Common Pathway of Root Growth Control and Response to CLE Peptides Through Two Receptor Kinases in Arabidopsis.

Cell-cell communication is essential for plants to integrate developmental programs with external cues that affect their growth. Recent advances in plant signaling have uncovered similar molecular mechanisms in shoot, root, and vascular meristem signaling that involve receptor-like kinases and small...

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Publicado en:Genetics Vol. 208; no. 2; pp. 687 - 705
Autores principales: Racolta, Adriana, Nodine, Michael D., Davies, Kelli, Lee, Cameron, Rowe, Scott, Velazco, Yulemi, Wellington, Rachel, Tax, Frans E.
Formato: Journal Article
Publicado: Oxford University Press / USA Feb2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2018
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      pub: Oxford University Press / USA
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        10.1534/genetics.117.300148
        135448976
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        atl: A Common Pathway of Root Growth Control and Response to CLE Peptides Through Two Receptor Kinases in Arabidopsis.
      aug:
        au:
          Racolta, Adriana
          Nodine, Michael D.
          Davies, Kelli
          Lee, Cameron
          Rowe, Scott
          Velazco, Yulemi
          Wellington, Rachel
          Tax, Frans E.
        affil: University of Arizona, Tucson, Arizona 85721
      sug:
        subj:
          Receptors, Cell Surface Physiology
          Cell Proliferation
          Peptides
          Growth
          Plant Roots Physiology
          Plant Components
          Cell Division
          Cell Differentiation
          Genotype
          Cell Communication
          Plants
          Phosphotransferases
      ab: Cell-cell communication is essential for plants to integrate developmental programs with external cues that affect their growth. Recent advances in plant signaling have uncovered similar molecular mechanisms in shoot, root, and vascular meristem signaling that involve receptor-like kinases and small, secreted peptides. Here, we report that the receptor-like kinases TOAD2/ RPK2 and RPK1 regulate root growth by controlling cell proliferation and affecting meristem size. Two types of developmental alterations were observed upon exogenous CLE peptide application. The first type was detected in all plants treated, and comprise increased proliferative activity of cells in the stem cell niche and a delay of progression in differentiation of daughter cells. The second type was changes specific to the genotypes that are sensitive to CLE-driven root meristem inhibition and include a large decrease in the occurrence of cell divisions in longitudinal files, correlating with shorter meristems and cessation of root growth. The root meristems of toad2/rpk2 mutant plants are insensitive to the inhibitory effect of CLE17 peptide treatment, consistent with TOAD2/RPK2 function as a receptor for CLE peptides. In addition, a strong reduction in the expression of RPK1 protein upon CLE treatment, dependent on TOAD2/RPK2, suggests that these two RLKs mediate CLE signaling in a common pathway to control root growth.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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