Acute ischemic stroke patients with diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score ≤ 5 can benefit from endovascular treatment: a single-center experience and literature review.

Purpose: The recommendation strength of the guidelines for mechanical thrombectomy among patients with large pre-treatment core infarct is weak. We evaluated the safety and outcome of endovascular treatment for acute ischemic stroke with diffusion-weighted imaging-Alberta Stroke Program Early Comput...

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Published in:Neuroradiology Vol. 61; no. 4; pp. 451 - 460
Main Authors: Song, Kangping, Guan, Min, Li, Wenxian, Jing, Zhen, Xie, Xiaomei, Shi, Changzheng, Liang, Jianye, Qiao, Hongyu, Huang, Li'an
Format: diagnostic images research systematic review tables/charts Journal Article
Published: Springer Nature Apr2019
Online Access:View this record in EBSCOhost
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      dt: Apr2019
      vid: 61
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      pub: Springer Nature
      place: New York, New York
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        135521893
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        10.1007/s00234-019-02177-1
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        atl: Acute ischemic stroke patients with diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score ≤ 5 can benefit from endovascular treatment: a single-center experience and literature review.
      aug:
        au:
          Song, Kangping
          Guan, Min
          Li, Wenxian
          Jing, Zhen
          Xie, Xiaomei
          Shi, Changzheng
          Liang, Jianye
          Qiao, Hongyu
          Huang, Li'an
        affil: Department of Neurology, Clinical Neuroscience Institute, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China
      sug:
        subj:
          Stroke Radiography
          Endovascular Procedures
          Outcome Assessment
          Magnetic Resonance Imaging Methods
          Clinical Assessment Tools
          Human
          Retrospective Design
          Scales
          Outcomes (Health Care)
          Reperfusion Methods
          Systematic Review
          Stroke Patients
      ab: Purpose: The recommendation strength of the guidelines for mechanical thrombectomy among patients with large pre-treatment core infarct is weak. We evaluated the safety and outcome of endovascular treatment for acute ischemic stroke with diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) ≤ 5.Methods: Data on acute ischemic stroke patients with DWI-ASPECTS ≤ 5 who underwent endovascular treatment within 6 h, or presented an arterial spin labeling-DWI (ASL-DWI) mismatch within 12 h, at our center were retrospectively collected. We report the clinical characteristics and outcome of every patient, and review the relevant literature.Results: Among the 19 patients who were enrolled, all experienced successful reperfusion, and 10 achieved a favorable outcome (modified Rankin scale (mRS) ≤ 2). Two patients presented with symptomatic intracranial hemorrhage (sICH); both of them had a poor outcome (mRS > 2).Conclusion: Acute ischemic stroke patients with large DWI lesions caused by large vessel occlusion can achieve a favorable clinical outcome with endovascular treatment if recanalization is performed within 6 h, or after 6 h in case of an ASL-DWI mismatch.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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