Amplification of DNA damage-inducible transcript 3 (DDIT3) is associated with myxoid liposarcoma-like morphology and homologous lipoblastic differentiation in dedifferentiated liposarcoma.

Dedifferentiated liposarcoma is defined as progression of atypical lipomatous tumor/well-differentiated liposarcoma to a higher grade usually non-lipogenic sarcoma, with amplification of 12q13-15. This region contains several genes involved in liposarcoma pathogenesis, including MDM2, CDK4, and DDIT...

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Bibliographic Details

Published in:	Modern Pathology Vol. 32; no. 4; pp. 585 - 593
Main Authors:	Mantilla, Jose G., Ricciotti, Robert W., Chen, Eleanor Y., Liu, Yajuan J., Hoch, Benjamin L.
Format:	pictorial research tables/charts Journal Article
Published:	Elsevier B.V. Apr2019
Online Access:	View this record in EBSCOhost