Chemotherapy-induced pyoderma gangrenosum.
Pyoderma gangrenosum (PG) is a refractory, painful, non-infectious, ulcerative and inflammatory skin condition. Approximately 50% of patients with PG showed an existing systemic disease, such as inflammatory bowel conditions, haematological disorders, rheumatoid diseases or hepatopathies. Some patie...
| Publicado en: | World Council of Enterostomal Therapists Journal Vol. 39; no. 1; pp. 9 - 18 |
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| Autores principales: | , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Cambridge Publishing
Mar2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135659213&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135659213 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08194610 YUD jtl: World Council of Enterostomal Therapists Journal issn: 08194610 maglogo: N pubinfo: dt: Mar2019 vid: 39 iid: 1 pid: 66266 pub: Cambridge Publishing artinfo: ui: 135659213 135659213 135659213 10.33235/wcet.39.1.9-17 135659213 ppf: 9 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Chemotherapy-induced pyoderma gangrenosum. aug: au: Wai Kuen Lee, Michelle Kar Kay Chan, Steven Choi Ching Fong, Amy Wai Sze Ho, Kristie affil: Nurse Consultant, Wound and Stomal Therapy, Department of Surgery, Queen Mary Hospital, Hong Kong sug: subj: Chemotherapy, Cancer Adverse Effects Pyoderma Gangrenosum Chemically Induced Pyoderma Gangrenosum Diagnosis Female Middle Age Myelodysplastic Syndromes Drug Therapy Decitabine Therapeutic Use Decitabine Adverse Effects Methylprednisolone Therapeutic Use Cyclosporine Therapeutic Use Aged Male Leukemia, Myeloid, Chronic Drug Therapy Azacitidine Therapeutic Use Azacitidine Adverse Effects Pyoderma Gangrenosum Drug Therapy Pyoderma Gangrenosum Mortality Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Pyoderma gangrenosum (PG) is a refractory, painful, non-infectious, ulcerative and inflammatory skin condition. Approximately 50% of patients with PG showed an existing systemic disease, such as inflammatory bowel conditions, haematological disorders, rheumatoid diseases or hepatopathies. Some patients developed PG following acute trauma or injury in a process known as pathergy. In the other cases, PG is characterised by isolated skin lesions with unknown causes and classified as idiopathic. However, in recent decades, PG has been reported in patients treated with certain medications. In this manuscript, we report two cases of PG, which were triggered by chemotherapy in patients with myelodysplastic syndrome (MDS) and chronic myelomonocytic leukaemia (CMML). Le pyoderma gangrenosum (PG) est une affection cutanée réfractaire, douloureuse, non infectieuse, ulcérante et inflammatoire. Près de 50% des patients atteints de PG ont une maladie systémique telle qu'une maladie inflammatoire des intestins, des troubles hématologiques, une maladie rhumatoïde ou hépatique. Quelques patients développent un PG suite à un traumatisme ou une plaie aigue selon un processus pathologique connu. Dans d'autres cas, le PG est caractérisé par des lésions cutanées isolées dont la cause est inconnue, appelées alors idiopathiques. Cela dit, dans les dernières décennies, le PG a été décrit chez des patients suivant certains traitements médicamenteux. Dans cet article, nous présentons deux cas de patients atteints de PG, patients suivant des traitements de chimiothérapie - un pour un syndrome myélodysplasique (SMD) et l'autre pour une leucémie myélomonocytaire chronique (LMMC). pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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