Executive Functioning Moderates Responses to Appetitive Cues: A Study in Severe Alcohol Use Disorder and Alcoholic Liver Disease.

Aim To examine subjective and psychophysiological responses to appetitive cues during an alcohol cue reactivity task, and its relation to alcoholic liver disease and assess whether executive functioning is associated with appropriate regulation of cue-elicited responses in individuals with severe al...

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Publicado en:Alcohol & Alcoholism Vol. 54; no. 1; pp. 38 - 47
Autores principales: Logge, Warren B, Morley, Kirsten C, Haber, Paul S, Baillie, Andrew J
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Jan2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2019
      vid: 54
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      pub: Oxford University Press / USA
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        10.1093/alcalc/agy083
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        atl: Executive Functioning Moderates Responses to Appetitive Cues: A Study in Severe Alcohol Use Disorder and Alcoholic Liver Disease.
      aug:
        au:
          Logge, Warren B
          Morley, Kirsten C
          Haber, Paul S
          Baillie, Andrew J
        affil: Department of Psychology, NHMRC Centre of Research Excellence in Mental Health and Substance Use, Macquarie University, NSW, Australia
      sug:
        subj:
          Executive Function Evaluation
          Appetite
          Cues
          Liver Diseases, Alcoholic Psychosocial Factors
          Alcoholism Psychosocial Factors
          Severity of Illness
          Task Performance and Analysis
          Human
          Alcoholism Rehabilitation
          Neuropsychological Tests Methods
          Alcoholic Beverages
          Heart Rate Variability
          Treatment Duration
          Recovery
      ab: Aim To examine subjective and psychophysiological responses to appetitive cues during an alcohol cue reactivity task, and its relation to alcoholic liver disease and assess whether executive functioning is associated with appropriate regulation of cue-elicited responses in individuals with severe alcohol use disorder (AUD). Methods Seventeen treatment-seeking alcoholic liver disease patients and a control group of treatment-seeking severe AUD participants completed neuropsychological executive functioning measures (Stroop task; Trail-making test) and the cue reactivity task, whereby control (water) and alcohol beverage cues were presented, followed by respective recovery periods. Subjective alcohol craving and heart rate variability were recorded across the task. Results Overall cue reactivity and consequent recovery after cue offset during the cue reactivity task was observed, and alcoholic liver disease participants demonstrated a reduced overall recovery effect. Better Stroop performance related to greater overall and alcohol-specific cue reactivity within the control AUD group, and alcoholic liver disease participants showed dysfunctional activity regardless of executive functioning performance. No group differences in recovery effects according to executive functioning performance were seen. Conclusion Among patients with AUD, having alcoholic liver disease seems to reduce overall regulation of responses to eliciting cues. Executive functioning moderated the magnitude of responses during cue exposures in our AUD sample overall; having alcoholic liver disease did not appear to affect regulation related to executive functioning during recovery.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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