The Clinical Features of Painful Small‐Fiber Neuropathy Suggesting an Origin Linked to Primary Sjögren's Syndrome.

Objective: We attempted to determine whether clinical features could differentiate painful small‐fiber neuropathy related to primary Sj€ogren's syndrome (pSS‐SFN) from idiopathic SFN (idio‐SFN). Methods: Validated clinical questionnaires and neurophysiological investigations specific for pain and SF...

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Publicado en:Pain Practice Vol. 19; no. 4; pp. 426 - 435
Autores principales: Zouari, Hela G., Wahab, Abir, Ng Wing Tin, Sophie, Sène, Damien, Lefaucheur, Jean‐Pascal
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2019
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: The Clinical Features of Painful Small‐Fiber Neuropathy Suggesting an Origin Linked to Primary Sjögren's Syndrome.
      aug:
        au:
          Zouari, Hela G.
          Wahab, Abir
          Ng Wing Tin, Sophie
          Sène, Damien
          Lefaucheur, Jean‐Pascal
        affil: EA 4391, Faculty of Medicine, Paris‐Est‐Creteil University, Créteil France
      sug:
        subj:
          Small Fiber Neuropathy Symptoms
          Sjogren's Syndrome Etiology
          Sjogren's Syndrome Diagnosis
          Human
          Questionnaires
          Descriptive Statistics
          Neurophysiology
          Anxiety
          Pain
          Skin Physiology
          Restless Legs
      ab: Objective: We attempted to determine whether clinical features could differentiate painful small‐fiber neuropathy related to primary Sj€ogren's syndrome (pSS‐SFN) from idiopathic SFN (idio‐SFN). Methods: Validated clinical questionnaires and neurophysiological investigations specific for pain and SFN assessment were performed in 25 patients with pSS‐SFN and 25 patients with idio‐SFN. Results: Patients with idio‐SFN had more frequent severe burning sensations and higher mean anxiety scores and daily pain intensity compared to patients with pSSSFN. Conversely, patients with pSS‐SFN had reduced electrochemical skin conductance measured by Sudoscan_, and almost half of them had the sensation of walking on cotton wool. Conclusion: Our results suggest that idio‐SFN more specifically involved small sensory fibers than pSS‐SFN, in which subtle dysfunction of larger sensory fibers and damage of distal autonomic sudomotor innervation may occur. A practical algorithm is proposed to help to differentiate SFN associated with pSS from idio‐SFN, based on information very easy to obtain by clinical interview.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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