Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses.

Background: The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfo...

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Publicado en:BioMedical Engineering OnLine Vol. 18; no. 1
Autores principales: Petrini, Francesco M., Mazzoni, Alberto, Rigosa, Jacopo, Giambattistelli, Federica, Granata, Giuseppe, Barra, Beatrice, Pampaloni, Alessandra, Guglielmelli, Eugenio, Zollo, Loredana, Capogrosso, Marco, Micera, Silvestro, Raspopovic, Stanisa
Formato: Journal Article
Publicado: BioMed Central 4/8/2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: BioMed Central
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        atl: Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses.
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          Petrini, Francesco M.
          Mazzoni, Alberto
          Rigosa, Jacopo
          Giambattistelli, Federica
          Granata, Giuseppe
          Barra, Beatrice
          Pampaloni, Alessandra
          Guglielmelli, Eugenio
          Zollo, Loredana
          Capogrosso, Marco
          Micera, Silvestro
          Raspopovic, Stanisa
        affil: Neuroengineering Lab, Department of Health Sciences and Technology, Institute for Robotics and Intelligent Systems, ETH Zürich, TAN E 2, Tannenstrasse 1, 8092, Zurich, Switzerland
      sug:
        subj:
          Median Nerve Physiology
          Hand Innervation
          Prosthesis Design
          Algorithms
          Hand
          Motor Neurons
          Hand Physiology
          Fingers Physiology
          Ultrasonography
          Movement
          Muscles Physiology
          Female
          Male
          Fingers
          Scales
          Female
          Male
      ab: Background: The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfortunately, this choice is still restrained by the reduced knowledge of the dynamics of human efferent signals recorded from the nerves and associated to hand movements.Findings: To address this issue, in this work we acquired neural efferent activities from healthy subjects performing hand-related tasks using ultrasound-guided microneurography, a minimally invasive technique, which employs needles, inserted percutaneously, to record from nerve fibers. These signals allowed us to identify neural features correlated with force and velocity of finger movements that were used to decode motor intentions. We developed computational models, which confirmed the potential translatability of these results showing how these neural features hold in absence of feedback and when implantable intrafascicular recording, rather than microneurography, is performed.Conclusions: Our results are a proof of principle that microneurography could be used as a useful tool to assist the development of more effective hand prostheses.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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