Assessment of decreased left ventricular longitudinal deformation in asymptomatic patients with organic mitral regurgitation and preserved ejection fraction using tissue‐tracking mitral annular displacement by speckle‐tracking echocardiography

Background: Application of speckle‐tracking echocardiography (STE) provides rapid assessment of tissue‐tracking mitral annular displacement (TMAD). We investigated the value of TMAD for the assessment of decreased LV longitudinal deformation in asymptomatic patients with severe or moderate‐to‐severe...

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Published in:Echocardiography Vol. 36; no. 4; pp. 678 - 687
Main Authors: Teraguchi, Ikuko, Hozumi, Takeshi, Takemoto, Kazushi, Ota, Shingo, Kashiwagi, Manabu, Shimamura, Kunihiro, Shiono, Yasutsugu, Kuroi, Akio, Yamano, Takashi, Yamaguchi, Tomoyuki, Matsuo, Yoshiki, Ino, Yasushi, Kitabata, Hironori, Kubo, Takashi, Tanaka, Atsushi, Akasaka, Takashi
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell Apr2019
Online Access:View this record in EBSCOhost
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      dt: Apr2019
      vid: 36
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.14290
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        atl: Assessment of decreased left ventricular longitudinal deformation in asymptomatic patients with organic mitral regurgitation and preserved ejection fraction using tissue‐tracking mitral annular displacement by speckle‐tracking echocardiography
      aug:
        au:
          Teraguchi, Ikuko
          Hozumi, Takeshi
          Takemoto, Kazushi
          Ota, Shingo
          Kashiwagi, Manabu
          Shimamura, Kunihiro
          Shiono, Yasutsugu
          Kuroi, Akio
          Yamano, Takashi
          Yamaguchi, Tomoyuki
          Matsuo, Yoshiki
          Ino, Yasushi
          Kitabata, Hironori
          Kubo, Takashi
          Tanaka, Atsushi
          Akasaka, Takashi
        affil: Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama Japan
      sug:
        subj:
          Mitral Valve Insufficiency Surgery
          Mitral Valve Annuloplasty Methods
          Ventricular Ejection Fraction
          Postoperative Complications
          Ventricular Dysfunction, Left Risk Factors
          Ventricular Dysfunction, Left Ultrasonography
          Echocardiography Methods
          Human
          Severity of Illness
          Retrospective Design
          Univariate Statistics
          Logistic Regression
          Multiple Regression
          Odds Ratio
          Confidence Intervals
          Sensitivity and Specificity
      ab: Background: Application of speckle‐tracking echocardiography (STE) provides rapid assessment of tissue‐tracking mitral annular displacement (TMAD). We investigated the value of TMAD for the assessment of decreased LV longitudinal deformation in asymptomatic patients with severe or moderate‐to‐severe mitral regurgitation (MR) and preserved LV ejection fraction (LVEF). Methods: We retrospectively studied 50 patients with severe or moderate‐to‐severe organic MR and preserved LVEF (>60%) in whom global longitudinal strain (GLS) was successfully measured by STE. TMAD was quickly assessed in the apical four‐chamber view using STE. We calculated the percentage of TMAD to LV length from the midpoint of mitral annulus to the apex at end‐diastolic (%TMAD). The study population was divided into two groups: decreased GLS patients (>−20%; Group A) and preserved GLS patients (≤−20%; Group B). We examined whether %TMAD could be used as a diagnostic factor of decreased GLS. Results: %TMAD was significantly lower in Group A than Group B (12.5 ± 0.5 vs 16.8 ± 2.2, P < 0.0001). By univariate logistic regression analysis, %TMAD was a diagnostic factor of decreased GLS. By multiple regression analysis, %TMAD remained an independent diagnostic factor of decreased GLS (Odds ratio [OR] = 4.21, 95% confidence interval [CI] = 1.34–28.94, P < 0.0001). A cutoff value of %TMAD <14.6 had a sensitivity of 94% and specificity of 94% for the presence of decreased GLS. Conclusions: Tissue‐tracking mitral annular displacement is useful in the assessment of decreased LV longitudinal deformation in asymptomatic patients with severe or moderate‐to‐severe MR and preserved LVEF.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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