Integrating Active Learning and Transfer Learning for Carotid Intima-Media Thickness Video Interpretation.

Cardiovascular disease (CVD) is the number one killer in the USA, yet it is largely preventable (World Health Organization 2011). To prevent CVD, carotid intima-media thickness (CIMT) imaging, a noninvasive ultrasonography method, has proven to be clinically valuable in identifying at-risk persons b...

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Publicado en:Journal of Digital Imaging Vol. 32; no. 2; pp. 290 - 300
Autores principales: Zhou, Zongwei, Shin, Jae, Feng, Ruibin, Hurst, R. Todd, Kendall, Christopher B., Liang, Jianming
Formato: algorithm diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Apr2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2019
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      pub: Springer Nature
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        atl: Integrating Active Learning and Transfer Learning for Carotid Intima-Media Thickness Video Interpretation.
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        au:
          Zhou, Zongwei
          Shin, Jae
          Feng, Ruibin
          Hurst, R. Todd
          Kendall, Christopher B.
          Liang, Jianming
        affil: Arizona State University, 13212 E Shea Blvd, 85259, Scottsdale, AZ, USA
      sug:
        subj:
          Cardiovascular Diseases Diagnosis
          Risk Assessment Methods
          Carotid Intima-Media Thickness Methods
          Radiographic Image Interpretation, Computer-Assisted Education
          Human
          Carotid Intima-Media Thickness Economics
          Radiographic Image Interpretation, Computer-Assisted Methods
          Image Processing, Computer Assisted Methods
          Algorithms Utilization
          Machine Learning Methods
      ab: Cardiovascular disease (CVD) is the number one killer in the USA, yet it is largely preventable (World Health Organization 2011). To prevent CVD, carotid intima-media thickness (CIMT) imaging, a noninvasive ultrasonography method, has proven to be clinically valuable in identifying at-risk persons before adverse events. Researchers are developing systems to automate CIMT video interpretation based on deep learning, but such efforts are impeded by the lack of large annotated CIMT video datasets. CIMT video annotation is not only tedious, laborious, and time consuming, but also demanding of costly, specialty-oriented knowledge and skills, which are not easily accessible. To dramatically reduce the cost of CIMT video annotation, this paper makes three main contributions. Our first contribution is a new concept, called Annotation Unit (AU), which simplifies the entire CIMT video annotation process down to six simple mouse clicks. Our second contribution is a new algorithm, called AFT (active fine-tuning), which naturally integrates active learning and transfer learning (fine-tuning) into a single framework. AFT starts directly with a pre-trained convolutional neural network (CNN), focuses on selecting the most informative and representative AU s from the unannotated pool for annotation, and then fine-tunes the CNN by incorporating newly annotated AU s in each iteration to enhance the CNN's performance gradually. Our third contribution is a systematic evaluation, which shows that, in comparison with the state-of-the-art method (Tajbakhsh et al., IEEE Trans Med Imaging 35(5):1299–1312, 2016), our method can cut the annotation cost by >81% relative to their training from scratch and >50% relative to their random selection. This performance is attributed to the several advantages derived from the advanced active, continuous learning capability of our AFT method.
      pubtype: Academic Journal
      doctype:
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        diagnostic images
        equations & formulas
        research
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      ougenre: Article
    language: English
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