T2 mapping of cartilage and menisci at 3T in healthy subjects with knee malalignment: initial experience.
Purpose: To assess the relationship between knee alignment and T2 values of femorotibial cartilage and menisci in healthy subjects at 3 T.Materials and Methods: Thirty-six healthy subjects divided into three subgroups of 12 neutral, 12 varus, and 12 valgus alignment of the femorotibial joint were in...
| Publicado en: | Skeletal Radiology Vol. 48; no. 5; pp. 753 - 764 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
May2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135822113&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135822113 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: May2019 vid: 48 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 135822113 135822113 NLM30712122 10.1007/s00256-019-3164-0 NLM30712122 135822113 ppf: 753 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: T2 mapping of cartilage and menisci at 3T in healthy subjects with knee malalignment: initial experience. aug: au: Zhu, Jiangtao Hu, Ningfan Liang, Xiaoyun Li, Xiaojing Guan, Jian Wang, Yajuan Wang, Ligong affil: Department of Radiology, The Second Affiliated Hospital of Soochow University, 1055 San Xiang Road, 215004, Suzhou, Jiangsu Province, China sug: subj: Cartilage, Articular Research Subjects Magnetic Resonance Imaging Methods Knee Joint Bone Diseases Menisci, Tibial Male Female Adult Adult: 19-44 years Male Female ab: Purpose: To assess the relationship between knee alignment and T2 values of femorotibial cartilage and menisci in healthy subjects at 3 T.Materials and Methods: Thirty-six healthy subjects divided into three subgroups of 12 neutral, 12 varus, and 12 valgus alignment of the femorotibial joint were investigated on 3-T MR scanner using a 2D multi-echo turbo spin-echo (TSE) sequence for T2 mapping. Wilcoxon signed-rank test and analysis of covariance (ANCOVA) were performed to determine any statistically significant differences in subregional T2 values of femorotibial cartilage and menisci among the three subgroups of healthy subjects.Results: Lateral femoral anterior cartilage subregion (52 ± 3 ms, mean ± standard deviation; 53 ± 2 ms) had significantly higher T2 values (p < 0.05) than medial femoral anterior cartilage subregion (51 ± 2 ms; 51 ± 2 ms) in varus and valgus groups, respectively. There were statistically significant differences (p < 0.05) in T2 values of tibial central cartilage subregion between lateral and medical compartment among varus, valgus, and neutral subgroups. Lateral body segment of meniscus (41 ± 3 ms) had significantly higher (p < 0.05) T2 values than medial body segment (40 ± 2 ms) in the varus subgroup.Conclusions: Some degree of correlation between knee alignment and subregional T2 values of femorotibial cartilage and menisci exists in healthy subjects. These findings indicate that T2 mapping may be sensitive in assessing the load distribution pattern of human cartilage and menisci with knee alignment abnormality, which may be used as reference baseline when understanding the occurrence and progression of knee osteoarthritis. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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