Distribution of common BCR-ABL fusion transcripts and their impact on treatment response in Imatinib treated CML patients: A study from India.
Background: Philadelphia chromosome (Ph): Hallmark of CML is caused by reciprocal translocation between chromosomes 9 and 22 resulting in BCR-ABL fusion protein. Most commonly associated breakpoint with CML is M-bcr in exon 13 or exon 14, producing splice variant b2a2 or b3a2 respectively. The distr...
| Publicado en: | Indian Journal of Pathology & Microbiology Vol. 62; no. 2; pp. 256 - 261 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Apr-Jun2019
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| Acceso en línea: | Ver este registro en EBSCOhost |