Machine Learning Readmission Risk Modeling: A Pediatric Case Study.

Background. Hospital readmission prediction in pediatric hospitals has received little attention. Studies have focused on the readmission frequency analysis stratified by disease and demographic/geographic characteristics but there are no predictive modeling approaches, which may be useful to identi...

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Publicado en:BioMed Research International pp. 1 - 10
Autores principales: Wolff, Patricio, Graña, Manuel, Ríos, Sebastián A., Yarza, Maria Begoña
Formato: equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/15/2019
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
      issn: 23146133
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      dt: 4/15/2019
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        135886409
        135886409
        135886409
        10.1155/2019/8532892
        135886409
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        atl: Machine Learning Readmission Risk Modeling: A Pediatric Case Study.
      aug:
        au:
          Wolff, Patricio
          Graña, Manuel
          Ríos, Sebastián A.
          Yarza, Maria Begoña
        affil: Research Center on Business Intelligence, University of Chile, Beauchef 851, Of. 502, Santiago, Chile
      sug:
        subj:
          Readmission Evaluation
          Machine Learning Methods
          Hospitals, Pediatric Chile
          Emergency Service
          Human
          Chile
          Case Studies
          Readmission Economics
          Retrospective Design
          Predictive Research
          Algorithms
          Descriptive Statistics
          Funding Source
      ab: Background. Hospital readmission prediction in pediatric hospitals has received little attention. Studies have focused on the readmission frequency analysis stratified by disease and demographic/geographic characteristics but there are no predictive modeling approaches, which may be useful to identify preventable readmissions that constitute a major portion of the cost attributed to readmissions. Objective. To assess the all-cause readmission predictive performance achieved by machine learning techniques in the emergency department of a pediatric hospital in Santiago, Chile. Materials. An all-cause admissions dataset has been collected along six consecutive years in a pediatric hospital in Santiago, Chile. The variables collected are the same used for the determination of the child's treatment administrative cost. Methods. Retrospective predictive analysis of 30-day readmission was formulated as a binary classification problem. We report classification results achieved with various model building approaches after data curation and preprocessing for correction of class imbalance. We compute repeated cross-validation (RCV) with decreasing number of folders to assess performance and sensitivity to effect of imbalance in the test set and training set size. Results. Increase in recall due to SMOTE class imbalance correction is large and statistically significant. The Naive Bayes (NB) approach achieves the best AUC (0.65); however the shallow multilayer perceptron has the best PPV and f-score (5.6 and 10.2, resp.). The NB and support vector machines (SVM) give comparable results if we consider AUC, PPV, and f-score ranking for all RCV experiments. High recall of deep multilayer perceptron is due to high false positive ratio. There is no detectable effect of the number of folds in the RCV on the predictive performance of the algorithms. Conclusions. We recommend the use of Naive Bayes (NB) with Gaussian distribution model as the most robust modeling approach for pediatric readmission prediction, achieving the best results across all training dataset sizes. The results show that the approach could be applied to detect preventable readmissions.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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