Exact inter-discharge interval distribution of motor unit firing patterns with gamma model.

Inter-discharge interval distribution modeling of the motor unit firing pattern plays an important role in electromyographic decomposition and the statistical analysis of firing patterns. When modeling firing patterns obtained from automatic procedures, false positives and false negatives can be tak...

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Publicado en:Medical & Biological Engineering & Computing Vol. 57; no. 5; pp. 1159 - 1172
Autores principales: Navallas, Javier, Porta, Sonia, Malanda, Armando
Formato: Journal Article
Publicado: Springer Nature May2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2019
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      place: New York, New York
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        atl: Exact inter-discharge interval distribution of motor unit firing patterns with gamma model.
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        au:
          Navallas, Javier
          Porta, Sonia
          Malanda, Armando
        affil: Department of Electric, Electronic and Communication Engineering, Public University of Navarra, 31006, Pamplona, Navarra, Spain
      sug:
        subj:
          Signal Processing, Computer Assisted
          Electromyography Methods
          Models, Biological
          False Negative Results
          Electromyography Statistics and Numerical Data
          Probability
      ab: Inter-discharge interval distribution modeling of the motor unit firing pattern plays an important role in electromyographic decomposition and the statistical analysis of firing patterns. When modeling firing patterns obtained from automatic procedures, false positives and false negatives can be taken into account to enhance performance in estimating firing pattern statistics. Available models of this type, however, are only approximate and use Gaussian distributions, which are not strictly suitable for modeling renewal point processes. In this paper, the theory of point processes is used to derive an exact solution to the distribution when a gamma distribution is used to model the physiological firing pattern. Besides being exact, the solution provides a way to model the skewness of the inter-discharge distribution, and this may make it possible to obtain a better fit with available experimental data. In order to demonstrate potential applications of the model, we use it to obtain a maximum likelihood estimator of firing pattern statistics. Our tests found this estimator to be reliable over a wide range of firing conditions, whether dealing with real or simulated firing patterns, the proposed solution had better agreement than other models. Graphical Abstract Model of the MU firing pattern generation and detection: fT,1(τ), IDI PDF of the physiological firing pattern; fT(τ), IDI PDF after modeling undetected firings (false negatives); fS(τ), IDI PDF after modeling classification errors (false positives).
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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