BTS-DSN: Deeply supervised neural network with short connections for retinal vessel segmentation.

Background and Objective: The condition of vessel of the human eye is an important factor for the diagnosis of ophthalmological diseases. Vessel segmentation in fundus images is a challenging task due to complex vessel structure, the presence of similar structures such as microaneurysms and hemorrha...

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Publicado en:International Journal of Medical Informatics Vol. 126; pp. 105 - 114
Autores principales: Guo, Song, Wang, Kai, Kang, Hong, Zhang, Yujun, Gao, Yingqi, Li, Tao
Formato: research Journal Article
Publicado: Elsevier B.V. Jun2019
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Medical Informatics
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      dt: Jun2019
      vid: 126
      pid: 467
      pub: Elsevier B.V.
      place: New York, New York
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        136017564
        10.1016/j.ijmedinf.2019.03.015
        NLM31029251
        136017564
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        atl: BTS-DSN: Deeply supervised neural network with short connections for retinal vessel segmentation.
      aug:
        au:
          Guo, Song
          Wang, Kai
          Kang, Hong
          Zhang, Yujun
          Gao, Yingqi
          Li, Tao
        affil: Nankai University, Tianjin, China
      sug:
        subj:
          Retina Anatomy and Histology
          Neural Networks (Computer)
          Retina
          Human
          Algorithms
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Psychological Tests
      ab: Background and Objective: The condition of vessel of the human eye is an important factor for the diagnosis of ophthalmological diseases. Vessel segmentation in fundus images is a challenging task due to complex vessel structure, the presence of similar structures such as microaneurysms and hemorrhages, micro-vessel with only one to several pixels wide, and requirements for finer results.Methods: In this paper, we present a multi-scale deeply supervised network with short connections (BTS-DSN) for vessel segmentation. We used short connections to transfer semantic information between side-output layers. Bottom-top short connections pass low level semantic information to high level for refining results in high-level side-outputs, and top-bottom short connection passes much structural information to low level for reducing noises in low-level side-outputs. In addition, we employ cross-training to show that our model is suitable for real world fundus images.Results: The proposed BTS-DSN has been verified on DRIVE, STARE and CHASE_DB1 datasets, and showed competitive performance over other state-of-the-art methods. Specially, with patch level input, the network achieved 0.7891/0.8212 sensitivity, 0.9804/0.9843 specificity, 0.9806/0.9859 AUC, and 0.8249/0.8421 F1-score on DRIVE and STARE, respectively. Moreover, our model behaves better than other methods in cross-training experiments.Conclusions: BTS-DSN achieves competitive performance in vessel segmentation task on three public datasets. It is suitable for vessel segmentation. The source code of our method is available at: https://github.com/guomugong/BTS-DSN.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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