Image Processing Approach for Detection of Leukocytes in Peripheral Blood Smears.
Peripheral blood smear analysis is a gold-standard method used in laboratories to diagnose many hematological disorders. Leukocyte analysis helps in monitoring and identifying health status of a person. Segmentation is an important step in the process of automation of analysis which would reduce the...
| Publicado en: | Journal of Medical Systems Vol. 43; no. 5 |
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| Autores principales: | , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136129195&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136129195 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01485598 4N0 jtl: Journal of Medical Systems issn: 01485598 maglogo: N pubinfo: dt: May2019 vid: 43 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 136129195 136129195 136129195 10.1007/s10916-019-1219-3 136129195 ppct: 1 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Image Processing Approach for Detection of Leukocytes in Peripheral Blood Smears. aug: au: Hegde, Roopa B. Prasad, Keerthana Hebbar, Harishchandra Singh, Brij Mohan Kumar affil: School of Information Sciences, MAHE, Manipal, India sug: subj: Blood Analysis Cell Nucleus Cell Separation Methods Leukocytes Classification Image Processing, Computer Assisted Methods Automation Human Sensitivity and Specificity Descriptive Statistics Staining and Labeling Hematology Laboratories India Microscopy Equipment and Supplies Image Processing, Computer Assisted Evaluation Mathematics Image Enhancement Methods ab: Peripheral blood smear analysis is a gold-standard method used in laboratories to diagnose many hematological disorders. Leukocyte analysis helps in monitoring and identifying health status of a person. Segmentation is an important step in the process of automation of analysis which would reduce the burden on hematologists and make the process simpler. The segmentation of leukocytes is a challenging task due to variations in appearance of cells across the slide. In the proposed study, an automated method to detect nuclei and to extract leukocytes from peripheral blood smear images with color and illumination variations is presented. Arithmetic and morphological operations are used for nuclei detection and active contours method is for leukocyte detection. The results demonstrate that the proposed method detects nuclei and leukocytes with Dice score of 0.97 and 0.96 respectively. The overall sensitivity of the method is around 96%. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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