Mixed phenotypic acute leukemia.

Mixed phenotypic acute leukemias (MPALs) are a heterogeneous group of rare leukemias constituting about 1% to 5% of all leukemias. MPAL is defined as an acute leukemia that demonstrates expression of a combination of antigens of different lineages so that it is not possible to assign a single lineag...

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Bibliographic Details
Published in:Baylor University Medical Center Proceedings Vol. 31; no. 1; pp. 90 - 92
Main Authors: Krause, John R., Findeis, Sarah
Format: case study pictorial tables/charts Journal Article
Published: Taylor & Francis Ltd Jan-Mar2018
Online Access:View this record in EBSCOhost
Description
Summary:Mixed phenotypic acute leukemias (MPALs) are a heterogeneous group of rare leukemias constituting about 1% to 5% of all leukemias. MPAL is defined as an acute leukemia that demonstrates expression of a combination of antigens of different lineages so that it is not possible to assign a single lineage to that leukemia. These leukemias have been characterized by relative therapeutic resistance. We present a case of a woman with an acute MPAL diagnosed as a B/myeloid leukemia.