Automatic Nasopharyngeal Carcinoma Segmentation Using Fully Convolutional Networks with Auxiliary Paths on Dual-Modality PET-CT Images.

Nasopharyngeal carcinoma (NPC) is prevalent in certain areas, such as South China, Southeast Asia, and the Middle East. Radiation therapy is the most efficient means to treat this malignant tumor. Positron emission tomography–computed tomography (PET-CT) is a suitable imaging technique to assess thi...

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Publicado en:Journal of Digital Imaging Vol. 32; no. 3; pp. 462 - 471
Autores principales: Zhao, Lijun, Lu, Zixiao, Jiang, Jun, Zhou, Yujia, Wu, Yi, Feng, Qianjin
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-018-00173-0
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        atl: Automatic Nasopharyngeal Carcinoma Segmentation Using Fully Convolutional Networks with Auxiliary Paths on Dual-Modality PET-CT Images.
      aug:
        au:
          Zhao, Lijun
          Lu, Zixiao
          Jiang, Jun
          Zhou, Yujia
          Wu, Yi
          Feng, Qianjin
        affil: School of Biomedical Engineering, Southern Medical University, 510515, Guangzhou, China
      sug:
        subj:
          Nasopharyngeal Neoplasms Diagnosis
          Tomography, Emission-Computed Utilization
          Tomography, Emission-Computed Methods
          Automation
          Neural Networks (Computer) Methods
          Image Processing, Computer Assisted
          Human
          Nasopharyngeal Neoplasms Therapy
          Radiotherapy Utilization
          Time Factors
          Costs and Cost Analysis
          China
          Validation Studies
      ab: Nasopharyngeal carcinoma (NPC) is prevalent in certain areas, such as South China, Southeast Asia, and the Middle East. Radiation therapy is the most efficient means to treat this malignant tumor. Positron emission tomography–computed tomography (PET-CT) is a suitable imaging technique to assess this disease. However, the large amount of data produced by numerous patients causes traditional manual delineation of tumor contour, a basic step for radiotherapy, to become time-consuming and labor-intensive. Thus, the demand for automatic and credible segmentation methods to alleviate the workload of radiologists is increasing. This paper presents a method that uses fully convolutional networks with auxiliary paths to achieve automatic segmentation of NPC on PET-CT images. This work is the first to segment NPC using dual-modality PET-CT images. This technique is identical to what is used in clinical practice and offers considerable convenience for subsequent radiotherapy. The deep supervision introduced by auxiliary paths can explicitly guide the training of lower layers, thus enabling these layers to learn more representative features and improve the discriminative capability of the model. Results of threefold cross-validation with a mean dice score of 87.47% demonstrate the efficiency and robustness of the proposed method. The method remarkably outperforms state-of-the-art methods in NPC segmentation. We also validated by experiments that the registration process among different subjects and the auxiliary paths strategy are considerably useful techniques for learning discriminative features and improving segmentation performance.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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