Diagnostic performance of MRI- versus MDCT-categorized T3cd/T4 for identifying high-risk stage II or stage III colon cancers: a pilot study.

Purpose: The aim of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI)-categorized T3cd/T4 tumors for identifying high-risk stage II or stage III cancer in patients with curatively resectable colon cancer in comparison to that of multidetector computed tomogra...

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Publicado en:Abdominal Radiology Vol. 44; no. 5; pp. 1675 - 1686
Autores principales: Park, Soo Yeun, Kim, Hye Jin, Park, Jun Seok, Choi, Gyu-Seog, Cho, Seung Hyun, Lee, Min A., Kim, Won Hwa, Lee, So Mi, Shin, Kyung-Min, Kim, Hye Jung, Kim, Gab Chul, Yoon, Ghilsuk, Kim, See Hyung
Formato: Journal Article
Publicado: Springer Nature May2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2019
      vid: 44
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      pub: Springer Nature
      place: New York, New York
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        136404889
        10.1007/s00261-018-1822-7
        136404889
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        atl: Diagnostic performance of MRI- versus MDCT-categorized T3cd/T4 for identifying high-risk stage II or stage III colon cancers: a pilot study.
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        au:
          Park, Soo Yeun
          Kim, Hye Jin
          Park, Jun Seok
          Choi, Gyu-Seog
          Cho, Seung Hyun
          Lee, Min A.
          Kim, Won Hwa
          Lee, So Mi
          Shin, Kyung-Min
          Kim, Hye Jung
          Kim, Gab Chul
          Yoon, Ghilsuk
          Kim, See Hyung
        affil: Colorectal Cancer Centre, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, 807 Hoguk-ro, Buk-gu, 41404, Daegu, Republic of Korea
      sug:
      ab: Purpose: The aim of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI)-categorized T3cd/T4 tumors for identifying high-risk stage II or stage III cancer in patients with curatively resectable colon cancer in comparison to that of multidetector computed tomography (MDCT). Materials and Methods: Thirty-eight patients with histopathologically indicated adenocarcinomas prospectively underwent MRI of the colon. Two radiologists independently and retrospectively assessed for T-category, including T3 substage (≤ T3ab vs. ≥ T3cd). The diagnostic accuracies and interreader agreements between assessments using each modality were compared using a pairwise comparison of receiver-operating characteristic curves and a weighted κ statistic, respectively. Results: Twenty-nine patients (76.3%) were histopathologically diagnosed with high-risk stage II or stage III colon cancer. The false-positive rate with MRI was lower than that with MDCT (0% vs. 7.9% for reader 1, 2.6% vs. 10.6% for reader 2). The diagnostic performance of MRI was better than that of MDCT across both readers (AUC: 0.707 vs. 0.506 [P = 0.032] for reader 1, 0.651 vs. 0.485 [P = 0.055] for reader 2). Moreover, MRI interreader agreement for the assessment of T3cd/T4 was significantly better than that of MDCT (κ = 0.821 vs. 0.391 [P = 0.017]). Conclusion: The diagnostic performance of MR imaging of the colon may be better than that of MDCT for identifying high-risk stage II or stage III cases. Particularly, colon MRI reduced the false-positive rate and improved the interreader agreement, although further studies with a larger sample size are required.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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