Day-Night Activity in Hospitalized Children after Major Surgery: An Analysis of 2271 Hospital Days.
Objectives: To characterize the day-night activity patterns of children after major surgery and describe differences in children's activity patterns between the pediatric intensive care unit (PICU) and inpatient floor setting.Study Design: In this prospective observational study, we characterized th...
| Publicado en: | Journal of Pediatrics Vol. 209; pp. 190 - 191 |
|---|---|
| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Elsevier B.V.
Jun2019
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136419399&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136419399 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00223476 04M jtl: Journal of Pediatrics issn: 00223476 maglogo: N pubinfo: dt: Jun2019 vid: 209 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 136419399 136419399 NLM30885646 136419399 10.1016/j.jpeds.2019.01.054 NLM30885646 136419399 ppf: 190 ppct: 1 formats: tig: atl: Day-Night Activity in Hospitalized Children after Major Surgery: An Analysis of 2271 Hospital Days. aug: au: Kudchadkar, Sapna R. Aljohani, Othman Johns, Jordan Leroux, Andrew Alsafi, Eman Jastaniah, Ebaa Gottschalk, Allan Shata, Nehal J. Al-Harbi, Ahmad Gergen, Daniel Nadkarni, Anisha Crainiceanu, Ciprian affil: Department of Anesthesiology and Critical Care Medicine, Charlotte R. Bloomberg Children's Center, Johns Hopkins University School of Medicine, Baltimore, MD sug: subj: Surgery, Operative Hospitalization Circadian Rhythm Child Time Factors Human Child, Preschool Prospective Studies Male Accelerometry Postoperative Period Adolescence Infant, Newborn Infant Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Funding Source Child: 6-12 years Child, Preschool: 2-5 years Adolescent: 13-18 years Infant, Newborn: birth-1 month Infant: 1-23 months Male Female ab: Objectives: To characterize the day-night activity patterns of children after major surgery and describe differences in children's activity patterns between the pediatric intensive care unit (PICU) and inpatient floor setting.Study Design: In this prospective observational study, we characterized the daytime activity ratio estimate (DARE; ratio between mean daytime activity [08:00-20:00] and mean 24-hour activity [00:00-24:00]) for children admitted to the hospital after major surgery. The study sample included 221 infants and children ages 1 day to 17 years admitted to the PICU at a tertiary, academic children's hospital. Subjects were monitored with continuous accelerometry from postoperative day 1 until hospital discharge. The National Health and Nutrition Examination Survey accelerometry data were utilized for normative data to compare DARE in a community sample of US children to hospitalized children.Results: The mean DARE over 2271 hospital days was 57.8%, with a significant difference between the average DARE during PICU days and inpatient floor days (56% vs 61%, P < .0001). The average subject DARE ranged from 43% to 73%. In a covariate-adjusted mixed effects model, PICU location, lower age, orthopedic or urologic surgery, and intubation time were associated with decreased DARE. Hospitalized children had significantly lower DARE than the National Health and Nutrition Examination Survey subjects in all age groups studied, with the largest difference in the youngest PICU group analyzed (6-9 years; 59% vs 75%, P < .0001). A subset analysis of children older than 2 years (n = 144) showed that DARE was <50% on 15% of hospital days.Conclusions: Children hospitalized after major surgery experience disruptions in day-night activity patterns during their hospital stay that may reflect disturbances in circadian rhythm. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|