Overall and subgroup prevalence of pyoderma gangrenosum among patients with hidradenitis suppurativa: A population-based analysis in the United States.
Background: Hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) are reported to coexist, although the prevalence of PG among patients with HS has not been systematically evaluated.Objective: To evaluate PG prevalence among patients with HS.Methods: Cross-sectional analysis of adults with PG...
| Publicado en: | Journal of the American Academy of Dermatology Vol. 80; no. 6; pp. 1533 - 1538 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
Jun2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136462071&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136462071 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Jun2019 vid: 80 iid: 6 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 136462071 136462071 NLM30738122 10.1016/j.jaad.2019.02.004 NLM30738122 136462071 ppf: 1533 ppct: 5 formats: tig: atl: Overall and subgroup prevalence of pyoderma gangrenosum among patients with hidradenitis suppurativa: A population-based analysis in the United States. aug: au: Tannenbaum, Rachel Strunk, Andrew Garg, Amit affil: Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra Northwell, New Hyde Park, New York sug: subj: Hidradenitis Suppurativa Epidemiology Aged Young Adult Skin Ulcer Epidemiology Adult Middle Age United States Adolescence Pyoderma Gangrenosum Epidemiology Prevalence Cross Sectional Studies Aged: 65+ years Adult: 19-44 years Middle Aged: 45-64 years Adolescent: 13-18 years ab: Background: Hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) are reported to coexist, although the prevalence of PG among patients with HS has not been systematically evaluated.Objective: To evaluate PG prevalence among patients with HS.Methods: Cross-sectional analysis of adults with PG among patients with HS and patients without HS through use of electronic health records data from a population-based sample of 55 million patients.Results: The prevalence of PG among 68,232 patients with HS was 0.18% (125 of 68,232), compared with 0.01% (1835 of 31,435,166) among those without HS (P < .0001). Prevalence was markedly higher among patients with HS and Crohn's disease (CD) (3.68%) than among patients with HS but without CD (0.12%). The odds of having PG were 21.14 (95% confidence interval [CI], 17.51-25.51) times greater among patients with HS than among those without HS. Patients with HS with CD had 12.38 (95% CI, 9.15-16.74) times the odds of having PG than did patients without HS but with CD. Among patients without CD, compared with patients without HS, those with HS had 26.51 (95% CI, 21.07-33.36) times the odds of having PG.Limitations: We could not establish HS phenotype among those having coexistent PG, nor could we distinguish syndromic from nonsyndromic cases.Conclusion: Patients with HS have an increased prevalence of PG, regardless of CD status. Painful ulcerations among patients with HS warrant additional evaluation for PG. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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