Development and evaluation of a jaw-tracking system for mice: reconstruction of three-dimensional movement trajectories on an arbitrary point on the mandible.

Background: Mastication is one of the most fundamental functions for the conservation of life. The demand for devices for evaluating stomatognathic function, for instance, recording mandibular movements or masticatory muscle activities using animal models, has been increasing in recent years to eluc...

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Publicado en:BioMedical Engineering OnLine Vol. 18; no. 1; pp. 1 - 15
Autores principales: Moriuchi, Emi, Hamanaka, Ryo, Koga, Yoshiyuki, Fujishita, Ayumi, Yoshimi, Tomoko, Yasuda, Go, Kohara, Haruka, Yoshida, Noriaki
Formato: Journal Article
Publicado: BioMed Central 5/16/2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 5/16/2019
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      pub: BioMed Central
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        10.1186/s12938-019-0672-z
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        136502456
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        atl: Development and evaluation of a jaw-tracking system for mice: reconstruction of three-dimensional movement trajectories on an arbitrary point on the mandible.
      aug:
        au:
          Moriuchi, Emi
          Hamanaka, Ryo
          Koga, Yoshiyuki
          Fujishita, Ayumi
          Yoshimi, Tomoko
          Yasuda, Go
          Kohara, Haruka
          Yoshida, Noriaki
        affil: Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, 852-8588, Nagasaki, Japan
      sug:
        subj:
          Tomography, X-Ray Computed
          Movement
          Mandible Physiology
          Mandible
          Imaging, Three-Dimensional
          Mice
          Kinematics
          Animals
      ab: Background: Mastication is one of the most fundamental functions for the conservation of life. The demand for devices for evaluating stomatognathic function, for instance, recording mandibular movements or masticatory muscle activities using animal models, has been increasing in recent years to elucidate neuromuscular control mechanisms of mastication and to investigate the etiology of oral motor disorders. To identify the fundamental characteristics of the jaw movements of mice, we developed a new device that reconstructs the three-dimensional (3D) movement trajectories on an arbitrary point on the mandible during mastication.Methods: First, jaw movements with six degrees of freedom were measured using a motion capture system comprising two high-speed cameras and four reflective markers. Second, a 3D model of the mandible including the markers was created from micro-computed tomography images. Then, the jaw movement trajectory on the certain anatomical point was reproduced by integrating the kinematic data of the jaw movements with the geometric data of the mandible.Results: The 3D movements at any points on the mandible, such as the condyle, molar, and incisor during mastication, could be calculated and visualized with an accuracy > 0.041 mm in 3D space. The masticatory cycle was found to be clearly divided into three phases, namely, the opening, closing, and occlusal phases in mice.Conclusions: The proposed system can reproduce and visualize the movements of internal anatomical points such as condylar points precisely by combining kinematic data with geometric data. The findings obtained from this system could facilitate our understanding of the pathogenesis of eating disorders or other oral motor disorders when we could compare the parameters of stomatognathic function of normal mice and those of genetically modified mice with oral behavioral dysfunctions.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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