Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study.

Purpose: Despite advance in renal replacement therapy (RRT), patients with chronic end-stage renal disease (ESRD) face various limitations, and renal transplantation (Tx) is the treatment that impacts most on quality of life (QoL). This study aimed to assess changes in QoL in a cohort of ESRD dialys...

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Publicado en:Quality of Life Research Vol. 28; no. 6; pp. 1485 - 1496
Autores principales: de Brito, Daniela Cristina Sampaio, Machado, Elaine Leandro, Reis, Ilka Afonso, Moreira, Daniela Pena, Nébias, Thiago Henrique Mascarenhas, Cherchiglia, Mariângela Leal
Formato: Journal Article
Publicado: Springer Nature Jun2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11136-019-02113-z
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        atl: Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study.
      aug:
        au:
          de Brito, Daniela Cristina Sampaio
          Machado, Elaine Leandro
          Reis, Ilka Afonso
          Moreira, Daniela Pena
          Nébias, Thiago Henrique Mascarenhas
          Cherchiglia, Mariângela Leal
        affil: Grupo de Pesquisa em Economia e Saúde, Belo Horizonte, Minas Gerais, Brazil
      sug:
        subj:
          Kidney Failure, Chronic Psychosocial Factors
          Kidney Transplantation Psychosocial Factors
          Quality of Life Psychosocial Factors
          Kidney Failure, Chronic Therapy
          Hemodialysis Psychosocial Factors
          Renal Replacement Therapy Psychosocial Factors
          Prospective Studies
          Adult
          Survivors
          Emotions
          Middle Age
          Male
          Mental Health
          Female
          Social Participation
          Questionnaires
          Short Form-36 Health Survey (SF-36)
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: Despite advance in renal replacement therapy (RRT), patients with chronic end-stage renal disease (ESRD) face various limitations, and renal transplantation (Tx) is the treatment that impacts most on quality of life (QoL). This study aimed to assess changes in QoL in a cohort of ESRD dialysis patients.Methods: Sociodemographic, clinical, nutritional, lifestyle, and QoL data were collected from 712 patients at baseline (time 1) and after 10 years of follow-up (time 2) for patients surviving. The QoL was assessed through the 36-Item Short Form Health Survey (SF-36) and the multiple linear regression model was used to analyze the factors associated with change in QoL.Results: A total of 205 survivors were assessed and distributed into three groups according to current RRT (Dialysis-Dialysis, Dialysis-Tx, and Dialysis-Tx-Dialysis). At time 1, only age was significantly different among groups; at time 2, transplant patients sustained greater social participation, job retention, and improvement in SF-36 scores. The factors associated with change in QoL were more time on dialysis interfering negatively on physical functioning (p = 0.002), role-physical limitations (p  = 0.002), general health (p  = 0.007), social functioning (p = 0.02), role-emotional (p = 0.003), and physical components ( p = 0.002); non-participation in social groups at times 1 and 2 reducing vitality (p = 0.02) scores; and having work at time 2, increasing vitality (p = 0.02) and mental health (p  = 0.02) scores.Conclusions: QoL was shown to be dynamic throughout the years of RRT, transplantation being the treatment with more benefits to the ESRD. More time on dialysis and limited social and occupational routine were associated with a reduction in QoL.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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