The development of spasticity with age in 4,162 children with cerebral palsy: a register-based prospective cohort study.
Background and purpose — Spasticity is often regarded as a major cause of functional limitation in children with cerebral palsy (CP). We analyzed the spasticity development with age in the gastrosoleus muscle in children with CP. Children and methods — This is a longitudinal cohort study of 4,162 ch...
| Publicado en: | Acta Orthopaedica Vol. 90; no. 3; pp. 286 - 292 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Medical Journals Sweden AB
Jun2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136537844&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136537844 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17453674 1BVL jtl: Acta Orthopaedica issn: 17453674 maglogo: N pubinfo: dt: Jun2019 vid: 90 iid: 3 pid: 59195 pub: Medical Journals Sweden AB artinfo: ui: 136537844 136537844 136537844 10.1080/17453674.2019.1590769 136537844 ppf: 286 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The development of spasticity with age in 4,162 children with cerebral palsy: a register-based prospective cohort study. aug: au: Lindén, Olof Hägglund, Gunnar Rodby-Bousquet, Elisabet Wagner, Philippe affil: Department of Clinical Sciences, Lund, Orthopedics, Lund University, Sweden sug: subj: Muscle Spasticity Risk Factors Cerebral Palsy Complications Gastrocnemius Muscle Pathology Age Factors Human Prospective Studies Registries, Disease Sweden Disease Surveillance Program Evaluation Scales Infant, Newborn Infant Child, Preschool Child Adolescence Sex Factors Data Analysis, Statistical Methods Male Female Infant, Newborn: birth-1 month Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years Male Female ab: Background and purpose — Spasticity is often regarded as a major cause of functional limitation in children with cerebral palsy (CP). We analyzed the spasticity development with age in the gastrosoleus muscle in children with CP. Children and methods — This is a longitudinal cohort study of 4,162 children (57% boys) with CP born in 1990–2015, monitored using standardized follow-up examinations in the Swedish surveillance program for CP. The study is based on 57,953 measurements of spasticity of the gastrosoleus muscle assessed using the Ashworth scale (AS) in participants between 0 and 15 years of age. The spasticity was analyzed in relation to age, sex, and Gross Motor Function Classification System (GMFCS) levels using a linear mixed model. Development of spasticity with age was modeled as a linear spline. Results — The degree of spasticity increased in most children over the first 5 years of life. At 5 years of age, 38% had an AS level of ≥ 2. The spasticity then decreased for 65% of the children during the remaining study period. At 15 years of age only 22% had AS ≥ 2. The level of spasticity and the rate of increase and decrease before and after 5.5 years of age were higher in children at GMFCS IV–V. Interpretation — The degree of spasticity of the gastrosoleus muscle often decreases after 5 years of age, which is important for long-term treatment planning and should be considered in spasticity management. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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