Parallel visuomotor processing in the split brain: cortico-subcortical interactions.

We tested nine patients with callosal pathology in a simple reaction time task with and without redundant targets in the same or opposite visual hemifield. Four patients showed large facilitation (redundancy gain) in the presence of a redundant target, exceeding probability summation models (neural...

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Publicado en:Brain: A Journal of Neurology Vol. 123; no. 4; pp. 759 - 770
Autores principales: Iacoboni, M, Ptito, A, Weekes, N Y, Zaidel, E
Formato: research Journal Article
Publicado: Oxford University Press / USA Apr2000
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Brain: A Journal of Neurology
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      dt: Apr2000
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      pub: Oxford University Press / USA
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        atl: Parallel visuomotor processing in the split brain: cortico-subcortical interactions.
      aug:
        au:
          Iacoboni, M
          Ptito, A
          Weekes, N Y
          Zaidel, E
        affil: Brain Mapping Division, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90095-7085, USA
      sug:
        subj:
          Brain Physiopathology
          Dominance, Cerebral Physiology
          Psychomotor Performance
          Models, Biological
          Occipital Lobe Physiopathology
          Telencephalon Physiopathology
          Telencephalon Pathology
          Human
          Probability
          Magnetic Resonance Imaging
          Agenesis of Corpus Callosum
          Cerebral Cortex Physiopathology
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Clinical Assessment Tools
      ab: We tested nine patients with callosal pathology in a simple reaction time task with and without redundant targets in the same or opposite visual hemifield. Four patients showed large facilitation (redundancy gain) in the presence of a redundant target, exceeding probability summation models (neural summation). Five patients showed redundancy gain not exceeding probability models. Violation of probability models was not associated with a specific type of callosal lesion. Neural summation, which probably occurs at collicular level, may be modulated by cortical activity. To test this hypothesis, we used functional MRI. During detection of redundant simultaneous targets, activations in the extrastriate cortex were observed in a patient with callosal agenesis and redundancy gain violating probability models, but not in a patient with callosal agenesis and redundancy gain not exceeding probability models. We conclude that cortical activity in the extrastriate cortex may be a modulating factor in the magnitude of the redundancy gain during parallel visuomotor transforms.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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