Calculation difficulties in children of very low birthweight: a neural correlate.

Learning difficulties, including problems with numeracy, are common in Western populations. Many children with learning difficulty are survivors of preterm birth. Although some of these children have neurological disabilities, many are neurologically normal, and the latter group provides us with an...

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Publicado en:Brain: A Journal of Neurology Vol. 124; no. 9; pp. 1701 - 1708
Autores principales: Isaacs, E B, Edmonds, C J, Lucas, A, Gadian, D G
Formato: research Journal Article
Publicado: Oxford University Press / USA Sep2001
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2001
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      pub: Oxford University Press / USA
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        atl: Calculation difficulties in children of very low birthweight: a neural correlate.
      aug:
        au:
          Isaacs, E B
          Edmonds, C J
          Lucas, A
          Gadian, D G
        affil: MRC Childhood Nutrition Research Centre and Radiology and Physics Unit, Institute of Child Health, University College London, 30 Guilford Street,London WC1N 1EH, UK
      sug:
        subj:
          Infant, Very Low Birth Weight
          Parietal Lobe Abnormalities
          Cognition Disorders Pathology
          Learning Disorders Pathology
          Mathematics
          Intelligence Tests
          Human
          Adolescence
          Infant, Newborn
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Adolescent: 13-18 years
          Infant, Newborn: birth-1 month
      ab: Learning difficulties, including problems with numeracy, are common in Western populations. Many children with learning difficulty are survivors of preterm birth. Although some of these children have neurological disabilities, many are neurologically normal, and the latter group provides us with an important opportunity to investigate the neural bases of learning problems. We have conducted a neuroimaging study of adolescent children who had been born preterm at 30 weeks gestation or less, to investigate the relationship between brain structure and a specific difficulty in arithmetic calculation. Using voxel-based morphometry, we have been able to demonstrate that there is an area in the left parietal lobe where children without a deficit in calculation ability have more grey matter than those who do have this deficit. To our knowledge, this is the first report establishing a structural neural correlate of calculation ability in a group of neurologically normal individuals.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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