Pyoderma gangrenosum -- a guide to diagnosis and management.
Pyoderma gangrenosum (PG) is a reactive non-infectious inflammatory dermatosis falling under the spectrum of the neutrophilic dermatoses. There are several subtypes, with 'classical PG' as the most common form in approximately 85% cases. This presents as an extremely painful erythematous lesion whic...
| Publicado en: | Clinical Medicine Vol. 19; no. 3; pp. 224 - 229 |
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| Autores principales: | , , |
| Formato: | pictorial review tables/charts Journal Article |
| Publicado: |
Elsevier B.V.
May2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136584643&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136584643 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14702118 65GE jtl: Clinical Medicine issn: 14702118 maglogo: N pubinfo: dt: May2019 vid: 19 iid: 3 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 136584643 136584643 136584643 10.7861/clinmedicine.19-3-224 136584643 ppf: 224 ppct: 5 formats: tig: atl: Pyoderma gangrenosum -- a guide to diagnosis and management. aug: au: George, Christina Deroide, Florence Rustin, Malcolm affil: Dermatology registrar, Royal Free Hospital, London, UK sug: subj: Pyoderma Gangrenosum Diagnosis Pyoderma Gangrenosum Therapy Leg Pathology Skin Diseases, Vesiculobullous Persistent Vegetative State Peristomal Skin Care Diagnosis, Differential Skin Ulcer Diagnosis Severity of Illness Physicians Disease Progression Early Diagnosis Wound Healing Cicatrix ab: Pyoderma gangrenosum (PG) is a reactive non-infectious inflammatory dermatosis falling under the spectrum of the neutrophilic dermatoses. There are several subtypes, with 'classical PG' as the most common form in approximately 85% cases. This presents as an extremely painful erythematous lesion which rapidly progresses to a blistered or necrotic ulcer. There is often a ragged undermined edge with a violaceous/ erythematous border. The lower legs are most frequently affected although PG can present at any body site. Other subtypes include bullous, vegetative, pustular, peristomal and superficial granulomatous variants. The differential diagnosis includes all other causes of cutaneous ulceration as there are no definitive laboratory or histopathological criteria for PG. Underlying systemic conditions are found in up to 50% of cases and thus clinicians should investigate thoroughly for such conditions once a diagnosis of PG has been made. Treatment of PG remains largely anecdotal, with no national or international guidelines, and is selected according to severity and rate of progression. Despite being a well-recognised condition, there is often a failure to make an early diagnosis of PG. This diagnosis should be actively considered when assessing ulcers, as prompt treatment may avoid the complications of prolonged systemic therapy, delayed wound healing and scarring. pubtype: Academic Journal doctype: pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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