Bronchoscopy specimens in adults with AIDS. Comparative yields of cytology, histology and culture for diagnosis of infectious agents.
Bronchoscopy specimens from 183 known/suspected acquired immunodeficiency syndrome patients were evaluated for pathogens. In each case, transbronchial biopsies were evaluated and bronchoalveolar lavage material was cultured for viruses, fungi and mycobacteria and examined cytologically. A specimen w...
| Publicado en: | CHEST Vol. 98; no. 1; pp. 24 - 29 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
American College of Chest Physicians
1990 Jul
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136601396&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136601396 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00123692 1G4 jtl: CHEST issn: 00123692 maglogo: N pubinfo: dt: 1990 Jul vid: 98 iid: 1 pid: 2556 pub: American College of Chest Physicians place: Glenview, Illinois artinfo: ui: 136601396 136601396 NLM2163300 136601396 NLM2163300 136601396 ppf: 24 ppct: 5 formats: tig: atl: Bronchoscopy specimens in adults with AIDS. Comparative yields of cytology, histology and culture for diagnosis of infectious agents. aug: au: Weldon-Linne, C M Rhone, D P Bourassa, R affil: Department of Pathology, Illinois Masonic Medical Center Chicago 60637 sug: subj: Respiratory Tract Infections Diagnosis Acquired Immunodeficiency Syndrome Complications Bronchoscopy Opportunistic Infections Diagnosis Body Fluids Fungi Retrospective Design Mycobacterium Cryptococcus Human Biopsy Methods Respiratory Tract Infections Etiology Cytomegaloviruses Male Candida Female Body Fluids Microbiology Opportunistic Infections Etiology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Male Female ab: Bronchoscopy specimens from 183 known/suspected acquired immunodeficiency syndrome patients were evaluated for pathogens. In each case, transbronchial biopsies were evaluated and bronchoalveolar lavage material was cultured for viruses, fungi and mycobacteria and examined cytologically. A specimen was considered positive for a pathogen if detected by any one of the methods (TBB or BALC or culture). BALC was more sensitive for Pneumocystis carinii than TBB (90 of 92 vs 67 of 80 cases). TBB and BALC had poor sensitivities for cytomegalovirus detection (six of 79 and ten of 91 cases, respectively): 80 of 91 CMV cases were detected by culture only. Nineteen of 26 MB cases were positive by culture only: BALC and TBB detected only three of 26 and five of 23 cases, respectively. Three cryptococcosis cases were detected by culture only. One coccidioidomycosis case was positive by BALC and culture. Culture and BALC in combination detected 212 of 216 all significant pathogens. We believe that TBB is not routinely necessary in AIDS-related bronchoscopies in the absence of suspicion of neoplasia. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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