Clinical and sonographic characteristics of Warthin-like variant papillary thyroid carcinomas.
Aim: To summarize the clinical, ultrasonographic (US) and pathological characteristics of Warthin-like variant papillary thyroid carcinomas (WVPTC).Material and Methods: Medical records and US images of 32 cases of WVPTCs diagnosed between December, 2006 and September, 2018 were reviewed. Clinical,...
| Publicado en: | Medical Ultrasonography Vol. 21; no. 2; pp. 152 - 158 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Jun2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136619614&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136619614 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Jun2019 vid: 21 iid: 2 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 136619614 136619614 NLM31063518 10.11152/mu-1870 NLM31063518 136619614 ppf: 152 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Clinical and sonographic characteristics of Warthin-like variant papillary thyroid carcinomas. aug: au: Chun-ping Ning Ja Seung Koo Eun-Kyung Kim Suji Lee Ning, Chunping Koo, Ja Seung Kim, Eun-Kyung Lee, Suji affil: The Affiliated Hospital of Qingdao University, Medical College, Ultrasound Department, Seoul, Korea sug: subj: Thyroid Neoplasms Thyroid Neoplasms Pathology Neoplasms, Complex and Mixed Pathology Neoplasms, Complex and Mixed Male Retrospective Design Female Thyroid Gland Pathology Adult Thyroid Gland Neoplasms, Complex and Mixed Complications Aged Hyperthyroidism Complications Ultrasonography Methods Middle Age Thyroid Neoplasms Complications Psychological Tests Scales Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Aim: To summarize the clinical, ultrasonographic (US) and pathological characteristics of Warthin-like variant papillary thyroid carcinomas (WVPTC).Material and Methods: Medical records and US images of 32 cases of WVPTCs diagnosed between December, 2006 and September, 2018 were reviewed. Clinical, pathological and US characteristics of these cases were collected and summarized. ACR TI-RADS was followed during the analysis of the US features of the lesions. Results: Totally, 32 patients with 33 WVPTC nodules were reviewed. WVPTC was more often seen in female patients (27/32,84.4%) with a relatively high age (mean age, 51.0±10.8 years old). Hyperthyroidism was observed in 14 patients; 2 patients were diagnosed as subclinical hyperthyroidism and 1 patient as subclinical hypothyroidism. Abnormal thyroglobulin antibody was detected in 22 patients. Mean size of the nodule was 1.2±0.5 cm (range, 0.5~2.99 cm) on US. Pathologically, tumor margin of 63.6% carcinomas were infiltrative but most (72.9%) of the enrolled carcinomas were intra-thyroidal. Lymphocytic thyroiditis was detected in 87.5% (28/32) patients. On US, most WVPTCs were solid or almost complete solid (32/33, 97.0%) and very hypoechoic (26/33, 78.8%). Taller-than-wide shape (6/33, 18.2%) and punctate echogenic foci (9/33, 27.3%) were not popular. All the nodules were scored higher than 5 points according to the ACR TI-RADS, including 9 nodules that were classified into TR4 and 24 nodules as TR5. Follow-up information was available in 31 patients and no recurrence or distal metastasis was detected.Conclusions: WVPTC is a rare variant of PTCs with favorable outcomes. Very hypoechoic echogenicity, solid or almost complete solid composition are the vital indicators for biopsy, even though the nodule may be wider-than-tall and have a lack of punctuate echoic foci. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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