Regional Changes in Density and Microarchitecture in the Ultradistal Tibia of Female Recruits After U.S. Army Basic Combat Training.

Musculoskeletal injuries, such as stress fracture, are responsible for over 10-million lost-duty days among U.S. Army Soldiers. During Basic Combat Training (BCT), an 8- to 10-week program that transforms civilians into Soldiers, women are four times more likely than men to sustain a stress fracture...

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Publicado en:Calcified Tissue International Vol. 105; no. 1; pp. 68 - 77
Autores principales: Sundaramurthy, Aravind, Xu, Chun, Hughes, Julie M., Gaffney-Stomberg, Erin, Guerriere, Katelyn I., Popp, Kristin L., Bouxsein, Mary L., Reifman, Jaques, Unnikrishnan, Ginu
Formato: research Journal Article
Publicado: Springer Nature Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Regional Changes in Density and Microarchitecture in the Ultradistal Tibia of Female Recruits After U.S. Army Basic Combat Training.
      aug:
        au:
          Sundaramurthy, Aravind
          Xu, Chun
          Hughes, Julie M.
          Gaffney-Stomberg, Erin
          Guerriere, Katelyn I.
          Popp, Kristin L.
          Bouxsein, Mary L.
          Reifman, Jaques
          Unnikrishnan, Ginu
        affil: Department of Defense Biotechnology High Performance Computing Software Applications Institute, Fort Detrick, MD, USA
      sug:
        subj:
          Bone and Bones Pathology
          Tibia Pathology
          Bone Density Physiology
          Military Personnel
          Young Adult
          Human
          Exercise
          Adult
          Female
          Tomography, X-Ray Computed Methods
          Absorptiometry, Photon Methods
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Clinical Assessment Tools
          Scales
          Adult: 19-44 years
          Female
      ab: Musculoskeletal injuries, such as stress fracture, are responsible for over 10-million lost-duty days among U.S. Army Soldiers. During Basic Combat Training (BCT), an 8- to 10-week program that transforms civilians into Soldiers, women are four times more likely than men to sustain a stress fracture. In this work, we performed high-resolution peripheral quantitative computed tomography scans on the ultradistal tibia of 90 female recruits [age = 21.5 ± 3.3 (mean ± standard deviation) years] before the start of BCT and after 8 weeks into BCT. Then, we divided the scanned bone volume into four sectors-lateral, posterior, medial, and anterior-and computed the bone density and microarchitectural parameters in each of the four sectors pre- and post-BCT. We used linear mixed models to estimate the mean difference for bone density and microarchitectural parameters, while controlling for age, race, and pre-BCT body mass index. Our results revealed that the total volumetric bone mineral density, trabecular volumetric bone mineral density, and trabecular thickness increased (p < 0.05) in each of the four sectors. In addition, cortical thickness and trabecular bone volume/total volume increased in both medial and posterior sectors (p < 0.05). Overall, six and five out of nine parameters improved in the medial and posterior sectors, respectively, after BCT. In conclusion, the heightened physical activity during BCT led to the most beneficial bone adaptation in the medial and posterior sectors of the ultradistal tibia, which is indicative of higher loading in these sectors during activities performed in the course of BCT.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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