Quality evaluation of the emergency program of three contemporary cell-washing machines.

This study evaluates the efficiency of emergency programs used by three contemporary cell washers. Both time necessary to process a given amount of blood and quality of the processed blood are investigated. The Fresenius Kabi Smart, Haemonetics Elite and LivaNova Xtra were validated using bovine blo...

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Publicado en:Perfusion Vol. 34; no. 4; pp. 318 - 323
Autores principales: De Somer, Filip, Bernolet, Hendrik, Bouchez, Stefaan, Bové, Thierry
Formato: equations & formulas research tables/charts Journal Article
Publicado: Sage Publications, Ltd. May2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2019
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      pub: Sage Publications, Ltd.
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        atl: Quality evaluation of the emergency program of three contemporary cell-washing machines.
      aug:
        au:
          De Somer, Filip
          Bernolet, Hendrik
          Bouchez, Stefaan
          Bové, Thierry
        affil: Laboratory for Experimental Cardiac Surgery, Ghent University, Belgium
      sug:
        subj:
          Cell Separation Equipment and Supplies
          Blood Transfusion, Autologous Equipment and Supplies
          Time Factors
          Software Evaluation
          Product Evaluation
          Equipment Design
          Calibration Evaluation
          Descriptive Statistics
          Kruskal-Wallis Test
          One-Way Analysis of Variance
          Data Analysis Software
          Centrifugation
      ab: This study evaluates the efficiency of emergency programs used by three contemporary cell washers. Both time necessary to process a given amount of blood and quality of the processed blood are investigated. The Fresenius Kabi Smart, Haemonetics Elite and LivaNova Xtra were validated using bovine blood, with a starting hematocrit of 13% or 21%. For all devices, the pre-programmed emergency program was used. The total volume processed in the 13% hematocrit group was 358 ± 68 mL for Fresenius, 375 ± 308 mL for Haemonetics and 497 ± 87 mL for LivaNova. In the 21% hematocrit group, the volumes were 533 ± 60 mL, 713 ± 142 mL and 798 ± 96 mL, respectively, showing a statistical difference between the Fresenius and LivaNova (p = 0.02). In the 13% hematocrit group, the Fresenius processed 45 ± 15 mL blood/min, the Haemonetics 62 ± 8 mL blood/min and the LivaNova 66 ± 1.5 mL blood/min. The difference between the Fresenius and LivaNova was statistically significant (p = 0.04). In the 21% hematocrit group, the processing speed was 69 ± 4 mL blood/min, 62 ± 8 mL blood/min and 77 ± 5 mL blood/min for the Fresenius, LivaNova and Haemonetics, respectively (p = 0.25). No major differences in the elimination of potassium, albumin and total protein or in hemolytic index were observed. No major differences were observed between discontinuous and continuous systems with respect to processing speed and wash quality with a starting hematocrit of 21%. Minor differences in processing speed were observed with a starting hematocrit of 13%.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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