Preoperative evaluation of tumour consistency in pituitary macroadenomas: a machine learning-based histogram analysis on conventional T2-weighted MRI.

Purpose: To evaluate the potential value of machine learning (ML)-based histogram analysis (or first-order texture analysis) on T2-weighted magnetic resonance imaging (MRI) for predicting consistency of pituitary macroadenomas (PMA) and to compare it with that of signal intensity ratio (SIR) evaluat...

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Publicado en:Neuroradiology Vol. 61; no. 7; pp. 767 - 775
Autores principales: Zeynalova, Amalya, Kocak, Burak, Durmaz, Emine Sebnem, Comunoglu, Nil, Ozcan, Kerem, Ozcan, Gamze, Turk, Okan, Tanriover, Necmettin, Kocer, Naci, Kizilkilic, Osman, Islak, Civan
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2019
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00234-019-02211-2
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        atl: Preoperative evaluation of tumour consistency in pituitary macroadenomas: a machine learning-based histogram analysis on conventional T2-weighted MRI.
      aug:
        au:
          Zeynalova, Amalya
          Kocak, Burak
          Durmaz, Emine Sebnem
          Comunoglu, Nil
          Ozcan, Kerem
          Ozcan, Gamze
          Turk, Okan
          Tanriover, Necmettin
          Kocer, Naci
          Kizilkilic, Osman
          Islak, Civan
        affil: Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey
      sug:
        subj:
          Preoperative Care
          Adenoma, Pituitary Pathology
          Machine Learning
          Magnetic Resonance Imaging Methods
          Human
          Retrospective Design
          Cancer Patients
          Neural Networks (Computer)
          Image Processing, Computer Assisted
          ROC Curve
          Reproducibility of Results
          Algorithms
          Artificial Intelligence
      ab: Purpose: To evaluate the potential value of machine learning (ML)-based histogram analysis (or first-order texture analysis) on T2-weighted magnetic resonance imaging (MRI) for predicting consistency of pituitary macroadenomas (PMA) and to compare it with that of signal intensity ratio (SIR) evaluation. Methods: Fifty-five patients with 13 hard and 42 soft PMAs were included in this retrospective study. Histogram features were extracted from coronal T2-weighted original, filtered and transformed MRI images by manual segmentation. To achieve balanced classes (38 hard vs 42 soft), multiple samples were obtained from different slices of the PMAs with hard consistency. Dimension reduction was done with reproducibility analysis, collinearity analysis and feature selection. ML classifier was artificial neural network (ANN). Reference standard for the classifications was based on surgical and histopathological findings. Predictive performance of histogram analysis was compared with that of SIR evaluation. The main metric for comparisons was the area under the receiver operating characteristic curve (AUC). Results: Only 137 of 162 features had excellent reproducibility. Collinearity analysis yielded 20 features. Feature selection algorithm provided six texture features. For histogram analysis, the ANN correctly classified 72.5% of the PMAs regarding consistency with an AUC value of 0.710. For SIR evaluation, accuracy and AUC values were 74.5% and 0.551, respectively. Considering AUC values, ML-based histogram analysis performed better than SIR evaluation (z = 2.312, p = 0.021). Conclusion: ML-based T2-weighted MRI histogram analysis might be a useful technique in predicting the consistency of PMAs, with a better predictive performance than that of SIR evaluation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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