Performances of the IDEIA HpStAR Stool Antigen Test in Detection of Helicobacter pylori Infection Before and After Eradication Treatment in Algerian Children.

We aimed to evaluate in an Algerian pediatric population the diagnostic performances of the IDEIA HpStAR noninvasive stool antigen test (Oxoid, Cambridge, UK) to detect Helicobacter pylori infection before and after eradication therapy. A prospective study including 158 symptomatic Algerian children...

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Publicado en:Journal of Tropical Pediatrics Vol. 65; no. 3; pp. 210 - 217
Autores principales: Moubri, Mostefa, Burucoa, Christophe, Kalach, Nicolas, Larras, R Rezki, Nouar, Nouria, Mouffok, Fawsia, Arrada, Zakia
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Jun2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2019
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      pub: Oxford University Press / USA
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        atl: Performances of the IDEIA HpStAR Stool Antigen Test in Detection of Helicobacter pylori Infection Before and After Eradication Treatment in Algerian Children.
      aug:
        au:
          Moubri, Mostefa
          Burucoa, Christophe
          Kalach, Nicolas
          Larras, R Rezki
          Nouar, Nouria
          Mouffok, Fawsia
          Arrada, Zakia
        affil: Service de Pédiatrie, Hôpital N. Hamoud CHU Hussein Dey, Algiers, Algeria Laboratoire Algérien de Recherche sur Helicobacter (LARH), Algiers, Algeria
      sug:
        subj:
          Helicobacter Infections Diagnosis
          Helicobacter Pylori
          Helicobacter Infections Microbiology
          Antigens, Bacterial Analysis
          Immunoenzyme Techniques Methods
          Feces Microbiology
          Algerians
          Female
          Helicobacter Pylori Immunology
          Helicobacter Infections Immunology
          Male
          Helicobacter Infections Drug Therapy
          Child
          Predictive Value of Tests
          Sensitivity and Specificity
          Immunoenzyme Techniques Statistics and Numerical Data
          Antibiotics Therapeutic Use
          Prospective Studies
          Algeria
          Feces
          Breath Tests
          Human
          Child: 6-12 years
          Female
          Male
      ab: We aimed to evaluate in an Algerian pediatric population the diagnostic performances of the IDEIA HpStAR noninvasive stool antigen test (Oxoid, Cambridge, UK) to detect Helicobacter pylori infection before and after eradication therapy. A prospective study including 158 symptomatic Algerian children was conducted. Patients were initially diagnosed with invasive (culture, histology, and rapid urease test) and noninvasive tests (urea breath test and IDEIA HpStAR test). Infected patients were treated, and 101 were controlled after treatment with two invasive (culture and histology) and two noninvasive tests (urea breath test and IDEIA HpStAR test). In Algerian children, the IDEIA HpStAR test showed good performances for initial detection of H. pylori infection and also for subsequent control of eradication treatment. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of IDEIA HpStAR test before treatment were 93.6%, 100%, 100%, 87.3%, and 96%, respectively, and those after treatment were 100, 92.8, 78.6, 100, and 94.2%, respectively.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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