Potential of a machine-learning model for dose optimization in CT quality assurance.

Objectives: To evaluate machine learning (ML) to detect chest CT examinations with dose optimization potential for quality assurance in a retrospective, cross-sectional study.Methods: Three thousand one hundred ninety-nine CT chest examinations were used for training and testing of the feed-forward,...

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Publicado en:European Radiology Vol. 29; no. 7; pp. 3705 - 3714
Autores principales: Meineke, Axel, Rubbert, Christian, Sawicki, Lino M., Thomas, Christoph, Klosterkemper, Yan, Appel, Elisabeth, Caspers, Julian, Bethge, Oliver T., Kröpil, Patric, Antoch, Gerald, Boos, Johannes
Formato: Journal Article
Publicado: Springer Nature Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Potential of a machine-learning model for dose optimization in CT quality assurance.
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          Meineke, Axel
          Rubbert, Christian
          Sawicki, Lino M.
          Thomas, Christoph
          Klosterkemper, Yan
          Appel, Elisabeth
          Caspers, Julian
          Bethge, Oliver T.
          Kröpil, Patric
          Antoch, Gerald
          Boos, Johannes
        affil: Cerner HS Deutschland GmbH, 13629, Berlin, Germany
      sug:
        subj:
          Radiation Injuries Prevention and Control
          Radiography, Thoracic Standards
          Quality Assurance
          Thoracic Diseases Diagnosis
          Multidetector Computed Tomography Standards
          Cross Sectional Studies
          Aged
          Retrospective Design
          Female
          Young Adult
          Middle Age
          Adolescence
          Adult
          Aged, 80 and Over
          Radiation Dosage
          Male
          Ferrans and Powers Quality of Life Index
          Scales
          Aged: 65+ years
          Middle Aged: 45-64 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged, 80 & over
          Female
          Male
      ab: Objectives: To evaluate machine learning (ML) to detect chest CT examinations with dose optimization potential for quality assurance in a retrospective, cross-sectional study.Methods: Three thousand one hundred ninety-nine CT chest examinations were used for training and testing of the feed-forward, single hidden layer neural network (January 2016-December 2017, 60% male, 62 ± 15 years, 80/20 split). The model was optimized and trained to predict the volumetric computed tomography dose index (CTDIvol) based on scan patient metrics (scanner, study description, protocol, patient age, sex, and water-equivalent diameter (DW)). The root mean-squared error (RMSE) was calculated as performance measurement. One hundred separate, consecutive chest CTs were used for validation (January 2018, 60% male, 63 ± 16 years), independently reviewed by two blinded radiologists with regard to dose optimization, and used to define an optimal cutoff for the model.Results: RMSE was 1.71, 1.45, and 1.52 for the training, test, and validation dataset, respectively. The scanner and DW were the most important features. The radiologists found dose optimization potential in 7/100 of the validation cases. A percentage deviation of 18.3% between predicted and actual CTDIvol was found to be the optimal cutoff: 8/100 cases were flagged as suboptimal by the model (range 18.3-53.2%). All of the cases found by the radiologists were identified. One examination was flagged only by the model.Conclusions: ML can comprehensively detect CT examinations with dose optimization potential. It may be a helpful tool to simplify CT quality assurance. CT scanner and DW were most important. Final human review remains necessary. A threshold of 18.3% between the predicted and actual CTDIvol seems adequate for CT quality assurance.Key Points: • Machine learning can be integrated into CT quality assurance to improve retrospective analysis of CT dose data. • Machine learning may help to comprehensively detect dose optimization potential in chest CT, but an individual review of the results by an experienced radiologist or radiation physicist is required to exclude false-positive findings.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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