Development of the Initial Surveys for the All of Us Research Program.

Background: The All of Us Research Program is building a national longitudinal cohort and collecting data from multiple information sources (e.g., biospecimens, electronic health records, and mobile/wearable technologies) to advance precision medicine. Participant-provided information, collected via...

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Publicado en:Epidemiology Vol. 30; no. 4; pp. 597 - 609
Autores principales: Cronin, Robert M., Jerome, Rebecca N., Mapes, Brandy, Andrade, Regina, Johnston, Rebecca, Ayala, Jennifer, Schlundt, David, Bonnet, Kemberlee, Kripalani, Sunil, Goggins, Kathryn, Wallston, Kenneth A., Couper, Mick P., Elliott, Michael R., Harris, Paul, Begale, Mark, Munoz, Fatima, Lopez-Class, Maria, Cella, David, Condon, David, AuYoung, Mona
Formato: research Journal Article
Publicado: Lippincott Williams & Wilkins Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Development of the Initial Surveys for the All of Us Research Program.
      aug:
        au:
          Cronin, Robert M.
          Jerome, Rebecca N.
          Mapes, Brandy
          Andrade, Regina
          Johnston, Rebecca
          Ayala, Jennifer
          Schlundt, David
          Bonnet, Kemberlee
          Kripalani, Sunil
          Goggins, Kathryn
          Wallston, Kenneth A.
          Couper, Mick P.
          Elliott, Michael R.
          Harris, Paul
          Begale, Mark
          Munoz, Fatima
          Lopez-Class, Maria
          Cella, David
          Condon, David
          AuYoung, Mona
        affil: From the Department of Biomedical Informatics and Internal Medicine, Vanderbilt University Medical Center, Nashville, TN
      sug:
        subj:
          Surveys
          Factor Analysis
          Male
          Adult
          Female
          United States
          Qualitative Studies
          Human
          Middle Age
          Pilot Studies
          Adolescence
          Young Adult
          Aged
          Prospective Studies
          Aged, 80 and Over
          Translations
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Adolescent: 13-18 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: The All of Us Research Program is building a national longitudinal cohort and collecting data from multiple information sources (e.g., biospecimens, electronic health records, and mobile/wearable technologies) to advance precision medicine. Participant-provided information, collected via surveys, will complement and augment these information sources. We report the process used to develop and refine the initial three surveys for this program.Methods: The All of Us survey development process included: (1) prioritization of domains for scientific needs, (2) examination of existing validated instruments, (3) content creation, (4) evaluation and refinement via cognitive interviews and online testing, (5) content review by key stakeholders, and (6) launch in the All of Us electronic participant portal. All content was translated into Spanish.Results: We conducted cognitive interviews in English and Spanish with 169 participants, and 573 individuals completed online testing. Feedback led to over 40 item content changes. Lessons learned included: (1) validated survey instruments performed well in diverse populations reflective of All of Us; (2) parallel evaluation of multiple languages can ensure optimal survey deployment; (3) recruitment challenges in diverse populations required multiple strategies; and (4) key stakeholders improved integration of surveys into larger Program context.Conclusions: This efficient, iterative process led to successful testing, refinement, and launch of three All of Us surveys. Reuse of All of Us surveys, available at http://researchallofus.org, may facilitate large consortia targeting diverse populations in English and Spanish to capture participant-provided information to supplement other data, such as genetic, physical measurements, or data from electronic health records.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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