Transcript mutations of the alpha regulatory subunit of protein kinase A and up-regulation of the RNA-editing gene transcript in lupus T lymphocytes.
Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder characterised by diverse dysfunctions of immune effector cells, including proliferation and cytotoxicity. In T cells from patients with SLE, activity of type 1 protein kinase A isozymes is greatly reduced because of decreased e...
| Publicado en: | Lancet Vol. 360; no. 9336; pp. 842 - 850 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Lancet
9/14/2002
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| Acceso en línea: | Ver este registro en EBSCOhost |