Image Processing Technique for Age Estimation in Thai Adults by Histomorphometry of Decalcified Cortical Bone.

Objective: Age estimation is an important step for biological identification. Histomorphometric age estimation in humans is based on observation of microstructural changes in the cortical bone. Several studies have used undecalcified bone sections for histomorphometric age estimation. In Thailand, m...

Descripción completa

Detalles Bibliográficos
Publicado en:International Medical Journal Vol. 26; no. 3; pp. 209 - 213
Autores principales: Chompoophuenl, Hathaichanok, Mahakkanukrauh, Pasuk, Settakorn, Jongkolnee, Mekjaidee, Karnda, Prasitwattanaseree, Sukon, Thumthong, Wichan
Formato: pictorial research tables/charts Journal Article
Publicado: Japan International Cultural Exchange Foundation Jun2019
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=137024280&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 137024280
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        13412051
        23J1
      jtl: International Medical Journal
      issn: 13412051
      maglogo: N
    pubinfo:
      dt: Jun2019
      vid: 26
      iid: 3
      pid: 29386
      pub: Japan International Cultural Exchange Foundation
    artinfo:
      ui:
        137024280
        137024280
        137024280
        137024280
      ppf: 209
      ppct: 4
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Image Processing Technique for Age Estimation in Thai Adults by Histomorphometry of Decalcified Cortical Bone.
      aug:
        au:
          Chompoophuenl, Hathaichanok
          Mahakkanukrauh, Pasuk
          Settakorn, Jongkolnee
          Mekjaidee, Karnda
          Prasitwattanaseree, Sukon
          Thumthong, Wichan
        affil: Forensic Osteology Research Center, Faculty of Medicine and Graduate School, Chiang Mai University 50200, Thailand
      sug:
        subj:
          Image Processing, Computer Assisted
          Age Determination by Skeleton In Adulthood
          Staining and Labeling
          Cortical Bone Pathology
          Femur Pathology
          Human
          Thailand
          Cadaver
          Male
          Female
          Age Factors
          Sex Factors
          Death Etiology
          Collagen
          Multiple Regression
          Correlation Coefficient
          Adult
          Adult: 19-44 years
          Male
          Female
      ab: Objective: Age estimation is an important step for biological identification. Histomorphometric age estimation in humans is based on observation of microstructural changes in the cortical bone. Several studies have used undecalcified bone sections for histomorphometric age estimation. In Thailand, most hospitals provide facilities and equipment for decalcified methods. Thus, the aim of this study is to develop an age prediction equation using decalcified bone sections stained by picrosirius red in the Thai population. Design: Age at death estimation was analyzed histomorphometrically from the cortical bones of femurs. Materials and Methods: Femoral cortical bone was collected from 71 cadavers (49 males and 22 females) with known age, sex and cause of death. Tissue sections were decalcified and stained with picrosirius red. Histological variables were measured with pixels using an image processing technique and MATLAB program. The histological area was measured in five variables. In addition, this study attempted to develop one new variable for quantifying the measurement of bone collagen. Results: Stepwise multiple regression was employed to develop a predictive model of age estimation. The stepwise selection method in this study utilized the following three histological variables for the equation: the perimeter of Haversian canal, the percentage of lamellar bone area and collagen in the bone stained by picrosirius red. The multiple correlation coefficient and standard error of estimate were 0.906 and 8.26, respectively. Conclusion: The decalcifying procedure and staining method that is routinely employed in histopathology laboratories with image processing technique can assist with age at death estimations in Thailand.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N