Malocclusion in children and adolescents with Down syndrome: A systematic review and meta‐analysis.

Background: Previous studies have shown a high prevalence of malocclusion in people with Down syndrome (DS) compared to individuals without DS, but no systematic review to summarize the evidence on this topic has been performed thus far. Aim: To evaluate whether children/adolescents with DS are more...

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Publicado en:International Journal of Paediatric Dentistry Vol. 29; no. 4; pp. 524 - 542
Autores principales: Doriguêtto, Paulo Victor T., Carrada, Camila F., Scalioni, Flávia A. R., Abreu, Lucas G., Devito, Karina L., Paiva, Saul M., Ribeiro, Rosangela A.
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell Jul2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2019
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/ipd.12491
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        atl: Malocclusion in children and adolescents with Down syndrome: A systematic review and meta‐analysis.
      aug:
        au:
          Doriguêtto, Paulo Victor T.
          Carrada, Camila F.
          Scalioni, Flávia A. R.
          Abreu, Lucas G.
          Devito, Karina L.
          Paiva, Saul M.
          Ribeiro, Rosangela A.
        affil: Department of Social and Paediatric Dentistry, School of Dentistry, Universidade Federal de Juiz de Fora, Juiz de Fora Brazil
      sug:
        subj:
          Down Syndrome Physiopathology
          Malocclusion Risk Factors
          Malocclusion Risk Factors
          Risk Assessment
          Human
          Systematic Review
          Meta Analysis
          Child
          Adolescence
          Scales
          Confidence Intervals
          Malocclusion Diagnosis
          Descriptive Statistics
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: Background: Previous studies have shown a high prevalence of malocclusion in people with Down syndrome (DS) compared to individuals without DS, but no systematic review to summarize the evidence on this topic has been performed thus far. Aim: To evaluate whether children/adolescents with DS are more affected by malocclusion than those without DS. Design: A search was performed in seven electronic databases. The quality of the included studies was assessed using the Newcastle‐Ottawa Scale. The strength of the evidence from the selected studies was evaluated by the Grading of Recommendations Assessment, Development and Evaluation system. Results: Eleven publications were included in the systematic review and eight were meta‐analysed. The meta‐analysis showed that malocclusion was more prevalent in children/adolescents with DS for Angle Class III (risk difference [RD] = 0.40; confidence interval [CI] = 0.33, 0.46), posterior crossbite (risk ratio [RR] = 3.09; CI = 2.02, 4.73), anterior crossbite (RR = 2.18; CI = 1.41, 3.39), and anterior open bite (RD = 0.21; CI = 0.06, 0.36). Conclusion: The occurrence of malocclusion was higher in children/adolescents with DS compared to individuals without the syndrome. The strength of the evidence of the studies analysed, however, was considered moderate and low.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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