Percutaneous left ventricular assist device support during ablation of ventricular tachycardia: A meta‐analysis of current evidence.

Introduction: Catheter ablation of ventricular tachycardia (VT) can be an effective therapy to reduce VT burden, but often it is limited by the potential for hemodynamic instability. Percutaneous left ventricular assist devices (pLVADs) have been used to maintain hemodynamic support during VT ablati...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 30; no. 6; pp. 886 - 896
Autores principales: Luni, Faraz Khan, Zungsontiporn, Nath, Farid, Talha, Malik, Sonia Ali, Khan, Sobia, Daniels, James, Wu, Richard, Link, Mark S., Joglar, Jose A.
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2019
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Percutaneous left ventricular assist device support during ablation of ventricular tachycardia: A meta‐analysis of current evidence.
      aug:
        au:
          Luni, Faraz Khan
          Zungsontiporn, Nath
          Farid, Talha
          Malik, Sonia Ali
          Khan, Sobia
          Daniels, James
          Wu, Richard
          Link, Mark S.
          Joglar, Jose A.
        affil: Department of Cardiology, UT Southwestern Medical Center, Dallas Texas
      sug:
        subj:
          Heart Assist Devices Methods
          Catheter Ablation Methods
          Tachycardia, Ventricular Surgery
          Hemodynamics
          Human
          Meta Analysis
          Systematic Review
          PubMed
          Tachycardia, Ventricular Mortality
          Treatment Duration
          Treatment Outcomes
          Catheter Ablation Adverse Effects
          Risk Assessment
      ab: Introduction: Catheter ablation of ventricular tachycardia (VT) can be an effective therapy to reduce VT burden, but often it is limited by the potential for hemodynamic instability. Percutaneous left ventricular assist devices (pLVADs) have been used to maintain hemodynamic support during VT ablation but the evidence regarding its clinical impact has been inconclusive. Methods and Results: We sought to assess the clinical impact of pLVAD when used in VT ablation by conducting a meta‐analysis of the current evidence. We searched Pubmed and found nine observational studies that compared clinical outcomes of VT ablation in patients with pLVAD support to controls with no pLVAD support. The pooled data did not show a significant difference in mortality between both groups, nor a difference in acute procedural success or in recurrence of VT. There was also no difference in the number of patients receiving a cardiac transplant or being enrolled in the transplant list. Although there was no difference in the ablation time between the groups, patients in the pLVAD group had a longer total procedural time and more procedure‐related adverse effects. Conclusion: This meta‐analysis did not show clinical benefits from using pLVAD support during VT ablation, whereas it was associated with longer procedure times and more complications. This study was, however, limited by the observational nature of the data. In view of these data, the risk and benefit of pLVAD support during VT ablation should be considered on an individual basis.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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