Prolyl 4-Hydroxylase Domain Protein 3-Inhibited Smooth-Muscle-Cell Dedifferentiation Improves Cardiac Perivascular Fibrosis Induced by Obstructive Sleep Apnea.

Background. Intermittent hypoxia (IH) induced by obstructive sleep apnea (OSA) is a leading factor affecting cardiovascular fibrosis. Under IH condition, smooth muscle cells (SMAs) respond by dedifferentiation, which is associated with vascular remodelling. The expression of prolyl 4-hydroxylase dom...

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Detalles Bibliográficos
Publicado en:BioMed Research International pp. 1 - 13
Autores principales: Tong, Jiayi, Yu, Fu-chao, Li, Yang, Wei, Qin, Li, Chen, Zhen, Penghao, Zhang, Guanghao
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/27/2019
Acceso en línea:Ver este registro en EBSCOhost